ID A0A3P9DQN0_9CICH Unreviewed; 458 AA.
AC A0A3P9DQN0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
OS Maylandia zebra (zebra mbuna).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005037070.1, ECO:0000313|Proteomes:UP000265160};
RN [1] {ECO:0000313|Ensembl:ENSMZEP00005037070.1, ECO:0000313|Proteomes:UP000265160}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [2] {ECO:0000313|Ensembl:ENSMZEP00005037070.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
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DR RefSeq; XP_004551735.1; XM_004551678.2.
DR AlphaFoldDB; A0A3P9DQN0; -.
DR STRING; 106582.ENSMZEP00005037070; -.
DR Ensembl; ENSMZET00005038363.1; ENSMZEP00005037070.1; ENSMZEG00005027621.1.
DR GeneID; 101466041; -.
DR KEGG; mze:101466041; -.
DR CTD; 559721; -.
DR GeneTree; ENSGT00940000161045; -.
DR OrthoDB; 3031241at2759; -.
DR Proteomes; UP000265160; LG13.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008459; F:chondroitin 6-sulfotransferase activity; IEA:RHEA.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF72; SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022968}.
FT DOMAIN 115..434
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 458 AA; 52795 MW; E40E464435880BD4 CRC64;
MTSYDPKNST VELTLQREDL RMKTKYAIVF ICIVALVIIE KESNILSRVS DRLIQRQIPQ
QQDFSNITQK GSLMALKMLL SRLSGTKRDN SNFSEEEEEE ELDDLGTYSY AGGRKHVLLL
ATTRTGSSFV GEFFNQHGEN MFYLFEPLWH VERMLTPAAE ANNGTVLSGI YRDVLQGLFL
CDFSPLEKFI SPPPQDHVTP SLFRRESSLS LCEERVCSPV IRDVFERYHC KSRRCGPLNL
TLASESCLSK QHHAIKTVRV HQLDTLQPLV EDPRLDIKVI QLVRDPRAIL ASRMVAFSSK
YHTWKAWAQN GQVPEDDEEV KRLKGNCDHI RMSAEVGLSQ PHWLRNRYML VRYEDIALYP
MQKAEEMYKF AGIPFSSLAR EWILRNTQTT QKASGIYSTQ KNSSQQAEKW RFTIPFTLAQ
VVQRVCGPTM KLFGYRFVND ETTLTNKSIS LLEDRLFN
//
