ID   A0A3P9DR11_9CICH        Unreviewed;       369 AA.
AC   A0A3P9DR11;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Immunity related GTPase cinema {ECO:0000313|Ensembl:ENSMZEP00005037205.1};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005037205.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005037205.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P9DR11; -.
DR   Ensembl; ENSMZET00005038508.1; ENSMZEP00005037205.1; ENSMZEG00005027729.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          14..194
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   369 AA;  41186 MW;  62F14FBE04D34539 CRC64;
     MILLQQQREE TCDISLHIAI TGESGSGKST FVNAVRGLRN GDEGAAPTGA VERSKEPMPY
     FHPGYPNVTL WDLPGVGTMK YPAHKYLELV KFDRFDFFII VSDTGCREND VKLAQEIQKI
     NKKCYFVCSK IDNFMCDERR NEDFSAERSL TKMRENCVQG LREQGIVSPQ VFLVSSFEPN
     LYDFSLLQQT LDRDLPKNKR DTLLFIMANI NPEIIIKKKK AFQSRIKYWA GLSGTVAAVP
     VPGLSVAVDI GLMVRVVKGY VTDFSLDKSS LEKLAERTDV PHADLCAVIR SPLAGVEITP
     ELLMRVSTQL ACIAAFMTAE ESVRWIPVVG LVASACLSFT LTYKALNSFL DTLADDAQRV
     FEKALGLNY
//