ID   A0A3P9DR35_9CICH        Unreviewed;       392 AA.
AC   A0A3P9DR35;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Interferon-inducible GTPase 5-like {ECO:0000313|Ensembl:ENSMZEP00005037230.1};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005037230.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005037230.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3P9DR35; -.
DR   Ensembl; ENSMZET00005038533.1; ENSMZEP00005037230.1; ENSMZEG00005027747.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160}.
FT   DOMAIN          39..220
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   392 AA;  43695 MW;  BEF92F93C52E6BA6 CRC64;
     FLHADLLEIK EEINEALLKN DRPAAAAKIT ELMMKEKNIR LNIAITGESG AGKSTFVNAL
     RGMSDYDEGA APTGVTETIS EVTPYLHPNY PNVTSWDLPG IGTTRFPADK YLELVGFEKF
     DFFIIISDTL FTENDVKLSQ EIHRMKKKFY FVRSKIDNNI RAEGRKRDFS EEETLTKIRD
     DCIKGEYLVM SVKSPQVFLV SSFELHLYNF SLLHGTLDRD LPAHKRDALL RAMPNFNPEI
     ISKKKQALKS RVKYWATLSA AGAAVPVPCL SIDVDLVMLV GVVTDYVFAF GLDVPSLMRL
     SDRTGVPYAD LCAVIFSPLA AVKITKKLLI TVMAQLGAVA ALIAAEEVFR WIPFIGILVS
     AGLSGTTTYR ILKLILDKLA DDAHRVFERA LV
//