ID   A0A3P9DTD0_9CICH        Unreviewed;       318 AA.
AC   A0A3P9DTD0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Exonuclease domain-containing protein {ECO:0000259|SMART:SM00479};
OS   Maylandia zebra (zebra mbuna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex.
OX   NCBI_TaxID=106582 {ECO:0000313|Ensembl:ENSMZEP00005037995.1, ECO:0000313|Proteomes:UP000265160};
RN   [1] {ECO:0000313|Ensembl:ENSMZEP00005037995.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9DTD0; -.
DR   Ensembl; ENSMZET00005039394.1; ENSMZEP00005037995.1; ENSMZEG00005028405.1.
DR   GeneTree; ENSGT00390000013978; -.
DR   Proteomes; UP000265160; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR028881; PAN2_UCH_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR15728; DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2; 1.
DR   PANTHER; PTHR15728:SF0; PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2; 1.
DR   Pfam; PF00929; RNase_T; 1.
DR   Pfam; PF13423; UCH_1; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265160};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          114..288
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00479"
SQ   SEQUENCE   318 AA;  36478 MW;  42CC42637BA00E01 CRC64;
     AHILDAGAGG NLVAHIKVGE TYHQRKEGVS RQQWYLFNDF LIEFLLVYSF YVSWKVPAIL
     CYAKRNYHTK YDLRSECQHN QSEVKSDLYR TEKQSKTDAT FIPLTVSEMP QAGDLVVFKT
     NLTPECVRLQ EEAVLHSDGT KSTITPSQMS VGVPFIDDYI STQEQVVDYL TKYSGIEPGD
     LDATVSSKDV TTLKSTYLKL RFLIDAEVRF VGHGRQNDFR VINLVVPKDQ VIDTVHLFRL
     PYKRMISLNS LLGIFLVSLN IQGETHDSTE DSCTALKLYR KYLELYQEGG NHYVTKVLYE
     VYDKGFQLNW KVPDSDMR
//