ID   A0A3P9N1W6_POERE        Unreviewed;       576 AA.
AC   A0A3P9N1W6;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Myotubularin-related protein 9-like {ECO:0000313|Ensembl:ENSPREP00000003569.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000003569.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000003569.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000003569.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC       receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P9N1W6; -.
DR   STRING; 8081.ENSPREP00000003569; -.
DR   Ensembl; ENSPRET00000003624.1; ENSPREP00000003569.1; ENSPREG00000002553.1.
DR   GeneTree; ENSGT00940000163547; -.
DR   OMA; CASYPPA; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000002553; Expressed in head and 1 other cell type or tissue.
DR   CDD; cd13211; PH-GRAM_MTMR9; 1.
DR   CDD; cd14536; PTP-MTMR9; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR   InterPro; IPR030564; Myotubularin_fam.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR10807:SF52; MYOTUBULARIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR   Pfam; PF06602; Myotub-related; 1.
DR   Pfam; PF21098; PH-GRAM_MTMR6-like; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT   DOMAIN          124..499
FT                   /note="Myotubularin phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51339"
SQ   SEQUENCE   576 AA;  66503 MW;  3CEEBB0F461D5A78 CRC64;
     MEFSDHIKTA NVEDVVLRQP LHPPSRGTLC ITGHHLLFSD REEGSSRQIL LLLRNIDAIE
     KRTPGSSGTI TIKCKDLRVL QLDIPGMEQC LNIAHSIETL SCLDNVSEMY PFFYRPNDLS
     LREQWGLSTP EKHYTQIKEL HKKWRLSSVN KTYSVCPSYP PVVIVPNSID DETLKKVAKF
     RQGGRFPVLC YYHRKNGMVI MRSSQPLTGA NKKRCKEDEL LLQVVIEDSD KGFIIDTRSS
     QQVQQARMTG GGFESKSCYS RWKRLHKQME RGKALQESLI KLVEACGDES HNVDRWLSKL
     ENSKWLSHVQ TALSAAGLLV ECVERDGHSA LVHGYEGTDC TLLICTLAQL IMDPSCRTLE
     GFLALLDREW LQAGHPFQQR CAHSAYSHAR LQQESPIFLL LLDCVWQLWR QFPLALGFSE
     ALLLRLANEV YASDYGTFLC NNDQERCALE VKDRTHCLFQ ALLRPPERDY YSNPLYEPNE
     LAIWPSVHPQ SLQLWRGFFL RWTQQARHLE AVQEEIRSMV IEWHRVTQRK MTRWNSQESC
     NADTPQENPR VLITGEDDFQ PLFAQNYLYL VDIEHF
//