ID A0A3P9NCM6_POERE Unreviewed; 728 AA.
AC A0A3P9NCM6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Scm polycomb group protein homolog 1 {ECO:0000313|Ensembl:ENSPREP00000007272.1};
GN Name=SCMH1 {ECO:0000313|Ensembl:ENSPREP00000007272.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000007272.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000007272.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000007272.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR RefSeq; XP_008429359.1; XM_008431137.2.
DR RefSeq; XP_008429361.1; XM_008431139.2.
DR AlphaFoldDB; A0A3P9NCM6; -.
DR STRING; 8081.ENSPREP00000007272; -.
DR Ensembl; ENSPRET00000007363.1; ENSPREP00000007272.1; ENSPREG00000005008.1.
DR GeneID; 103477834; -.
DR KEGG; pret:103477834; -.
DR CTD; 22955; -.
DR GeneTree; ENSGT00940000157999; -.
DR OMA; NKEFCSM; -.
DR OrthoDB; 2908161at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000005008; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF68; POLYCOMB PROTEIN SCMH1; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 2.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT REPEAT 38..136
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 144..246
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 663..728
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 253..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..414
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 79780 MW; 9EF138F4BE30A504 CRC64;
MRKPVPQKAL EWKDARIIKH ARSGRPSRVP SQYQAGHFSW EKYLKETGAT AAPSSCFKQS
PTPPLNEFKV GMKLEAQDPR NTTSTCIATV VGLTGSRLRL RLDGSDNKND FWRLVDSSEI
QPIGSCEKSG GMLQPPLGFR LNASSWPMFL LKTLNGAEMA PSRIFHKQEP PAPEQNSFQV
GMKLEAVDRK NPHFICPATV GALRGVEVLV TFDGWRGAFD YYCRYDSRDI FPVGWCSLTG
DNLQPPGTKA VLPKSLGTPT EGSVETPAMN PTPTVGRPPG QRGRKPGRRK TKITGPWSQK
PSTLVSQSVQ PGKDLEPIKI PKKRGPKPGS KLGWGKRDGW FEDSLTGPGR PAGPGRTRGR
LLASWAQRIA LQQAQAQAQA EPEQIKIPKK RGPKPGSKRK PRVQPNPVPT SPTSSTPEPD
TSTVPQDNAT IPNSALQAPT VCVYLNKYGK VGPHLDQRRI QQLPDHFGPG RASSVLQQCV
QACVDSAHNQ ATVFSCLKSG QGGEVISAFF DQQQHTLTLP TVSSVTYVLR FLEKLCHNLH
CDALFGSQPV ARGSGHYDSH SYSAERRGFG DTLTAGPGKG TKRFQQDFNG PLTSKLAKLP
RHSTDGENNV SALEHSKKIP LSPNSPPGLT PGLRSPSRLL HHNSSAGSFR ESPRPSGQDP
NLWTVEEVMQ YIRDIDPVLA PHANLFRKHE IDGKALLLLR SDVMMKYMGL KLGPALKLTF
HIDKLKRA
//
