ID   A0A3P9NCQ8_POERE        Unreviewed;       838 AA.
AC   A0A3P9NCQ8;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Semaphorin-4B-like {ECO:0000313|Ensembl:ENSPREP00000007345.1};
GN   Name=SEMA4B {ECO:0000313|Ensembl:ENSPREP00000007345.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000007345.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000007345.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000007345.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_008403023.1; XM_008404801.2.
DR   RefSeq; XP_017159597.1; XM_017304108.1.
DR   RefSeq; XP_017159598.1; XM_017304109.1.
DR   AlphaFoldDB; A0A3P9NCQ8; -.
DR   STRING; 8081.ENSPREP00000007345; -.
DR   Ensembl; ENSPRET00000007437.1; ENSPREP00000007345.1; ENSPREG00000005048.1.
DR   GeneID; 103462179; -.
DR   KEGG; pret:103462179; -.
DR   GeneTree; ENSGT00940000154870; -.
DR   OMA; ELPVANC; -.
DR   OrthoDB; 4266123at2759; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000005048; Expressed in caudal fin and 1 other cell type or tissue.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR002165; Plexin_repeat.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF14; SEMAPHORIN-4B; 1.
DR   Pfam; PF01437; PSI; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..838
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017974924"
FT   TRANSMEM        705..725
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          35..513
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   REGION          736..838
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        757..799
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   838 AA;  94053 MW;  577D6D59B8AE3925 CRC64;
     MCSVAVTIRR LLAAALLLAG GLESASETEE DVTPRISFSY NAKERSAKRF SVGGVFNYTS
     LLLSQEDDML YVGAREALFA LSLSDISKTK LQKNLTWGTP AGKRDECSFK GKNLETDCFN
     YIKILLRLNS THLYVCGTYS FSPVCAYINT STFTLARDEA GEVVTEDGRS RCPFNPEYKS
     TAIIVDGELY TGTVSNFQGN EPVIYKSLGQ GTALKTENSL KWLQDPVFVG STFIEESQPA
     GNPVGDDDKI YFFFSEAGKE FDFFDNTIVS RIARVCKGDR GGERVLQKKW TTFLKAQLLC
     SLPDDGFPFN IIQDMFVLKP TGDSWESTVF YGVFTSQWYK GASGSSAVCA FSMAQVEAAF
     NGRYREVNRE SQQWYTYNHP VPEPRPGACV TNHARQMGIQ SSLHMPDKVL NFVKDHFLMD
     SVIRSAPLLL KRSVRYTQIA VHKIQGMERA YDVLFIGTDD GKLHKAINVN DKMHIIEEMV
     LFAEPQPVQH IELDSQRGLL FVSSYSGLVE VPVANCSNYL SCGECVLSRD PYCAWTGRLC
     RDVRMAPPDS HWQQDVEEAD TSAICNSTVP FLRSARPAAS RAFRCKTITV PANTFRVLPC
     KLRSNLAQRK WRYSKDASQF LYETPEGNLV VVAQSDRTET YECWSEEEGF RQLLANYCIR
     AEPRQESTTL IGHSRTPHVA PDETIILPGE SRAEQAHTKT YWNELIVVCA LLAFSLVVFS
     LFVIYRNRDH MKSMLKQGEC PNMQQKKPRI VGKPTESLPL NGNNIPVSTS DHKGYQTLND
     NYICSTPTHE SSSPENSKSF SEASDRRPLN AKESHVEYSP TCPRPRVRLG SEIKDSIV
//