ID A0A3P9NFW9_POERE Unreviewed; 861 AA.
AC A0A3P9NFW9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Taste receptor type 1 member 3 {ECO:0000256|ARBA:ARBA00040705};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000008449.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000008449.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000008449.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family. TAS1R
CC subfamily. {ECO:0000256|ARBA:ARBA00038492}.
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DR RefSeq; XP_008406805.1; XM_008408583.2.
DR AlphaFoldDB; A0A3P9NFW9; -.
DR STRING; 8081.ENSPREP00000008449; -.
DR Ensembl; ENSPRET00000008547.1; ENSPREP00000008449.1; ENSPREG00000005769.1.
DR GeneID; 103464462; -.
DR KEGG; pret:103464462; -.
DR CTD; 83756; -.
DR GeneTree; ENSGT00940000160679; -.
DR OMA; WALGMKF; -.
DR OrthoDB; 4096532at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15290; 7tmC_TAS1R3; 1.
DR CDD; cd06363; PBP1_taste_receptor; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF435; TASTE RECEPTOR TYPE 1 MEMBER 3; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..861
FT /note="Taste receptor type 1 member 3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018259365"
FT TRANSMEM 576..596
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 641..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..703
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 735..756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..791
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 803..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 572..835
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 861 AA; 95757 MW; 04F7506B0FEF4CFA CRC64;
MASLLYLLCA LCWTFRPCCS VSSPEWFQNM TTNLFSLPGD VTLGGLFPIN QQSNSSGFIS
EPYSIKCESL NEYGLGLALV MKYAVDEING KQDILPGVKL GYKMYDTCRH SSIIVKPTIS
FLTEKTSNAL SVECNYTDYE TSISAVIGPY TSEMVSVIGK LLGFFLMPQI SYGATSDKFS
DNLLYPSFFR TVPSDKWQVD AMVQLMYEFN WTWVAVIGSE EEYGQSGVQQ FSKVAENKSV
CVAYQGLIPV YTDPGPAVQT IINNIKTTEV KVVIVFALPE PAAFFFEQVV QENLTGVWIA
SSSWIIHNRL ISIPKIKDIG TIIGFVDKLN SLDLLNNYTE TLLRKISEER ANNATIQPKS
HDPDNPCPQC WYLSPANITL VNDLAVKRLG FAVYSAVYSV AQALHTLLEC DSAGCNWRPD
SKIYPWKLLE VLRNTSVNIS GTILEFDKNG NPNVGYNLVE WIWETSGKVA FKNVGNYYQN
KLFINASRFE WHTENSTVPL STCSAQCADG QVRRVKGFHS CCYDCIDCLA GTFQANKDDI
QCAKCPERQW SNDRSTNCTA PIFEILGWDS DDALKIILAV LALLICQVSV AVVFLIHRGT
PLVKASGGVL TFLALLSLMG GCLSLFLFLG EPDDVVCRLQ LPLITIFQSV ALSIILSISL
QIFLVTEFPK KVAPHLRTLR GPGSWLFVLI CCSVQAGLCG WFVQEEPSLT AYKNNMEINF
MKTFLPCPVS PDKLAVMQGL NAAMALVSFM STFMAIKPHH QYNLARDITF STLIYCVIWV
IFIPVYTGLT ANILTVSKNK STVHVYFTLA GNLGLVVAYY FPKCYLLFKN PDSNTPEYFC
TFLEGVPPTP PQEEPEPPPA K
//
