ID A0A3P9NKK8_POERE Unreviewed; 378 AA.
AC A0A3P9NKK8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ring finger protein 13 {ECO:0000313|Ensembl:ENSPREP00000010115.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000010115.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000010115.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000010115.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_008405055.1; XM_008406833.2.
DR RefSeq; XP_008405056.1; XM_008406834.2.
DR AlphaFoldDB; A0A3P9NKK8; -.
DR STRING; 8081.ENSPREP00000010115; -.
DR Ensembl; ENSPRET00000010231.1; ENSPREP00000010115.1; ENSPREG00000006887.1.
DR GeneID; 103463470; -.
DR KEGG; pret:103463470; -.
DR CTD; 11342; -.
DR GeneTree; ENSGT00940000154942; -.
DR OMA; GHIVLIP; -.
DR OrthoDB; 5474929at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000006887; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd02123; PA_C_RZF_like; 1.
DR CDD; cd16796; RING-H2_RNF13; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR044744; ZNRF4/RNF13/RNF167_PA.
DR PANTHER; PTHR47168:SF6; PROTEASE-ASSOCIATED (PA) RING_U-BOX ZINC FINGER FAMILY PROTEIN; 1.
DR PANTHER; PTHR47168; RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 181..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 239..281
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 284..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..353
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 42228 MW; BCD54CA05757CEB8 CRC64;
MLLSLGMLML SATQVYTIFT VQLFAFLNLL PVEADIAAYS FDNKTETFDD MPARFGYRLP
SDGLKGFLIG ARPENACEPI EPPPRENMTG AFIVLIKRYD CNFDMKVLNA QKAGYKAAIV
HNVDSDDLIS MGSNDLDVLK QIVIPSVFVS ELTANALKDD YMYDKGGHLV LIPDFSLPLE
YYLIPFLIIV GICLILIVVF MITKFVQDRR RARRSRLRKD QLKKLPIHKF KKGDNYDVCA
ICLDEYEDGD KLRVLPCSHA YHSKCVDPWL TKTKKTCPVC KQKVVPSQGD SDSDSEEGDS
GPDENEVSES TPLLRSQAST SAHSFGTMSG ASRSEQDSSE YDDDDELGSS DSEEEVTVET
VVVQMQQPCS DEHDLPRA
//
