ID A0A3P9NNB1_POERE Unreviewed; 796 AA.
AC A0A3P9NNB1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Vitrin {ECO:0000313|Ensembl:ENSPREP00000011050.1};
GN Name=VIT {ECO:0000313|Ensembl:ENSPREP00000011050.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000011050.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000011050.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000011050.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008428498.1; XM_008430276.2.
DR AlphaFoldDB; A0A3P9NNB1; -.
DR Ensembl; ENSPRET00000011177.1; ENSPREP00000011050.1; ENSPREG00000007433.1.
DR GeneID; 103477275; -.
DR CTD; 5212; -.
DR GeneTree; ENSGT00940000159330; -.
DR OrthoDB; 2883115at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000007433; Expressed in head and 1 other cell type or tissue.
DR CDD; cd01472; vWA_collagen; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF23; VITRIN; 1.
DR Pfam; PF03815; LCCL; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00603; LCCL; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF69848; LCCL domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50820; LCCL; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..796
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018176347"
FT DOMAIN 33..126
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 411..596
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 613..782
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 167..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 86997 MW; C70D2E564D130E73 CRC64;
MIRSITVIFY AFLLSWACWA KPNGSKSKKP KQVVPDIECD VRAGKINLPE FIAKCPAHCK
ETKQQVYGTG VFASISSICN AAIHSGVITN AGGKVIVRKM AGQNVYKGSN SNGVRSLSLP
KWRESFVVSV GKPKKGVIYP STLDYAPSRP TYVKTGSKDT KLAAFTTLPP TTAPEATTTT
PEPTTTTAPT TTTTMPPPPP TTTKARAAVH KIRDAGSSHP YLAHVAAASS RQSQSAQGKS
PSQVFRGSSY PNRYPQRASA GLRRPEAGSA IRRQPSSPVG PALNRAPPER TPTTSQSNSA
FPRRDWPPSS YSRPDWFPGA RRPADVSYAV PDSGYAWSET ETPEMPAPRS TDLDGSHKMP
LHLPQGKVEP VDAWKQDANP YESGFSLREP EALPRAPEPP ASQGDPNCKV DLAFLMDGSW
SIGKRRFKIQ KDFLAEVAQV INVGMAGPMM GIIQYGDEPV TEISLRAHSS SKDVKSAIDK
IVQKGGMSNV GKALSYINKQ YFSDANGNRG GAPNVAVVLV DGWPTDKVEE ASRLARESGI
NIFFVTIEGP DENEKQNLVE ANFVDKAVCR TNGFFSLPVN SWFALRKAVQ PLVKRVCDTD
RLVCSKTCLN ANDIAFVIDG SSSVGTGNFR TVLQFVANVT REFEISDTDT RVGAVQYTYE
QRLEFAFGQY NNKAELLNAI KRINYWSGGT STGAAITFAA EQLFSKSKPN KRKIMIVITD
GRSYDDVRAP ALAVHRQGVI AYSIGIAWAA QDELEYIATD PDKEHSFFVD EFDNLYKYVT
KIIHNICQEF NSQPRN
//
