ID A0A3P9NQS3_POERE Unreviewed; 2631 AA.
AC A0A3P9NQS3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Tetratricopeptide repeat domain 28 {ECO:0000313|Ensembl:ENSPREP00000011909.1};
GN Name=TTC28 {ECO:0000313|Ensembl:ENSPREP00000011909.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000011909.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000011909.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000011909.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSPRET00000012042.1; ENSPREP00000011909.1; ENSPREG00000007988.1.
DR GeneTree; ENSGT00940000156428; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000007988; Expressed in caudal fin and 1 other cell type or tissue.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10098; RAPSYN-RELATED; 1.
DR PANTHER; PTHR10098:SF106; TETRATRICOPEPTIDE REPEAT PROTEIN 28; 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF13424; TPR_12; 9.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13176; TPR_7; 2.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 25.
DR SUPFAM; SSF48452; TPR-like; 7.
DR PROSITE; PS50005; TPR; 10.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 270..303
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 458..491
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 538..571
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 658..691
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 738..771
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 778..811
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1021..1054
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1101..1134
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1181..1214
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1221..1254
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1533..1879
FT /note="CHAT"
FT /evidence="ECO:0000259|Pfam:PF12770"
FT REGION 1718..1746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2187..2487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2573..2615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2263..2311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2312..2338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2362..2429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2443..2484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2573..2608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2631 AA; 285952 MW; 28B1C7BB924B3AA0 CRC64;
MIGKENHNIN SAQRKKKVSQ TVLQRVDHSS AHLTDTLWPD LGTLSFLCAR SRSAVATGGE
KEGEKRKEKK KEKDLTTWRT FLDESFSWTA YAAQLFVDFI WRLSTIFYDA KRTFFGQTLK
HFLLHTDTRT HTHTKNSTLN LQRLGWDETD KPLYKHTQSA RMEKQATLKE KFSVFGSRTA
GRPIRCVAVD DGSRCALSKA EFMEKVRQSN EACQRGDFQE AVRLYGDALQ ADPQNCILYS
NRSAAFLKLG QHQAALEDAE KACGLNPKWP KAYFRQGVAL QYLGRHADAL AAFASGLAQD
PKSLQLLVGM VEAAMKSPLR DSLEPTYQQL QKMKLDKSPF VVVSVIGQEL LTAGHHTASV
VVLEAALKIG TCSLKLRGSV FSALSSAHWS LGNTEKSLGY MQQDLEVAKT LGDQTGECRA
HGNLGSAFFS KGNYREALTN HRNQLVLAMK LKDREAASMA LSSLGHVYTA IGDYPNALAS
HKQCVLLAKQ SKDQLSEARE LGNMGAVYIA MGDFDNAVQC HEQHLGIAKA LENKREEARA
YSNLGSAYHY HRNFDKAMSY HTHVLELAQE LEEKSIEMRA YAGLGHAARC MQDLERAKQY
HEQQLSIAEG LKDRAAEGRA SSNLGIIHQM KGDYETALKL HKTHLAIAQE LNDYAAQGRA
YGNMGNAYNA LGAFDQAVRY HRQELQISME VNDRASQAST HGNLAVAYQA LGAHDRALQH
YQNHLNIARE LRDVQSEARA LGNLGNFHCS RGEFPQAVPY YEQYLRLSPE LQDMESEGKV
CHNLGYAHYC LGNYQDAVKY YEQDLALAKD LHDKLSQAKA YCNLGLAFKA LGDFTKAEEC
QKYLLSLAQS LNNAQARFRA LGNLGDIFVC KKDVTGAIQF YEQQLALAHQ VKERRMEACA
YAALGATYRL VQKYDKALGY HTQELEVYQE LGDVSGECKA HGHLAAVYMA LGKYAMAFKS
YEEQLELGRR LKDPVVEAQV YGNMGITKMN VGVMEEAIGY LEQQLATLQQ LSGNEAVMDR
GRAYGNLGDC YEALGDFEEA IKYYDQYLSV AQSLNRMQDQ EKAYRGLGNG HRAMGNLQQS
LVCFEKRLVV AHELGECGGK AQAYGELGAL HSQLGNYEQA ISCLERQLAI ARDTQDRLLE
GDASCGLGAV YQAMGEYETA LRCHQSDLEI AEEAGSTTRQ ARAYGNLGLT YESLGNYERA
VVFQEQHLSV AAQTNDLAAK TLAYGSLGRT HHALQNYSQA VMYLQEGLRL AEQLARREDE
AKIRHRLGLS LWASGNLEEA QHQLYRASAL FETIRHEAQH STDYKLSLFD LQTSCYQALQ
RVLVSLGHHD EALAVAERGR TRAFADLLVE RQTGQQDSDP YTPVTVEHIL DTVNSQRALV
LYFSMAAGYL YSWLLAPGAG ILKFHEVYLG EGVSEGGSDF QEGGGGGMVS SSSLEQHIAS
AREALGVESY YSRGCSSSET ESEAGDFLDQ QFEELNNKLN SVTDPTGFLR MVSRNNLFNR
SCQSMTSLFS NTMSPAKDGN SSLPRRSSNL GKPPLRALYD LLIAPMEGGL MHSSGPVGRH
RQLVMVLEGE LYLIPFALLK GSSSNEYLYE RFSLIAVPSI HGLGFSAKAH SRRPGPAPCG
GVSMAAVVGN PRLPSPVMDR WLWGPMPTAE EEALMVAELL GCQPLTGSSA TKERVMGALT
QAECAHFATH ISWKLAALVL TPNPECVPGG AGATVGVGTI GRGTSSRRGS SGRGRKGSVG
SGYTIPESLN MQDDGSDVES ICDSPPLQEF LLTAADILDL RLPVKLVVLG SYQESSSKVT
ADGVVGLTRA FLAAGAQCVL VSLWPVPVAA SKVFVHAFYS ALLNGTKASA ALADAMKTVQ
SSKQYSHPSN WAGYMLIGND VKLNSPSSLI GQALAEILQY PDRARDALRV LLHLVEKSLQ
RIQNGQRNSM YTSQQSVENK VGGVPGWQAL LTAVGFRLDS AGTGIPAAVF FPTADPGDRL
QQCSTTLQSL LGLPPPALQA LCKLITASEA GEQLINRLHQ VLVQLQTGEK EQDFSLLPIQ
VSISVQLWRL PGCHEFLAAL GFDLCEVGQE EVVLKTGKLA NRRTLHFALQ SLLALFDSTE
LPKRLSLDSS SSLESLASAQ SVSNPLPVGY SSLPFSPPCL DNQASDAISV YSLSSVTSSM
SFASKSDCDF LSHRQRGGAT AHYTVHKHPH VPRSRSSPQG AAAAGAGTRG DEEEYEGFSI
ISSEPLGSHC DSLPLPPGHS QRHHRGRGVG GSAGAGRGYM VSVSSRGSVS TPTSPVKTSL
LPSPNSPFQK VGKVNSSDTG ESDQSSTETD STVKSQEEKP VHLDPQELAQ KILEETHSHL
RAVSSLQRAG AEGGTGPAAA SARSGTFRSS ETSAFSRPNS SASGRAQSSP KPKPPSRSSS
LQKVSSGYNS PAVSESSQKD GSHPSPTLDS HAQFKLKYPS SPYSGHISRS PSNVSPSSGH
QSPAGSAPSP ALSYSSTGSA CSTSADAPDL DRLRRGVIDE KVQAIHNLKT FWTNAAAQQQ
QHLGPVKAIH STSGPIASAS RDVLSLLNLS PRHCSPHDAQ DSLELRELGL QSLDSGTKNS
SNGHHCSNPR KVAPSPTIST SSSPGARSIR LPAGNGYKFL SPGRFFPSSK C
//
