ID A0A3P9NSI6_POERE Unreviewed; 1144 AA.
AC A0A3P9NSI6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ankyrin repeat and FYVE domain containing 1 {ECO:0000313|Ensembl:ENSPREP00000012539.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000012539.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000012539.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000012539.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9NSI6; -.
DR STRING; 8081.ENSPREP00000012539; -.
DR Ensembl; ENSPRET00000012672.1; ENSPREP00000012539.1; ENSPREG00000008492.1.
DR GeneTree; ENSGT00940000156179; -.
DR OMA; WGLEQVV; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000008492; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18501; BACK_ANKFY1_Rank5; 1.
DR CDD; cd18303; BTB_POZ_Rank-5; 1.
DR CDD; cd15728; FYVE_ANFY1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 6.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR049765; ANFY1_BTB_POZ.
DR InterPro; IPR049764; ANFY1_FYVE.
DR InterPro; IPR049763; ANKFY1_BACK.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24178:SF9; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01363; FYVE; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 21.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 11.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 51..113
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REPEAT 349..382
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 474..506
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 517..549
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 596..628
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 629..661
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 744..776
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 845..877
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 880..912
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 913..945
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 946..979
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1018..1050
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1079..1139
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 728..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1144 AA; 125087 MW; 1DF4ECC18B0CB357 CRC64;
MQQKLADTER RCAVLAAQTS SQASASPASA DTFISRLLEF VANLYQQEHY SDLKVKVAGD
QYCAHKFVLA ARSDAWSLAN LASTAELDLT DCKAEVAMAM LRWVYTDELE LTEDDAFLIE
LMKLANRFQL HLLRERCEKG VMSSVNVRNC IRFYQTAEEL NASTLMNYCG EIIASHWDDL
RKEDFSTMSA QLLYKMIKSK TEYPLHKAIK IEREDVVFLY LIEMDSQLPG KLNELDNNGD
LALDLALSRK LEGIATTLVN NKADVDMVDQ SGWSLLHKAI QRGDEFASIF LIRHSAQVNA
ATVGAVETPL HLVCSFSPKK HTAEVMGSMA RIAEALLKAG ANPNMQNSKG RTPLHEAVAS
GNEAVFNQLL QCKQLDLELK DHEGSTALWL ALQHITMSSD LSVNPFEDDA PVVNGTSFDE
NGFAAQLIKR GSNPDAPDAT AGNCLMQRAA RAGNEAAALF LATHGAKVNH VNKWGESPLH
TACRCGLASL TAELLQQGAN PNLQTQKPLP EETNSVALQT PLHMAIAHNH PDVVSVILEQ
KANALHATNN LQIIPDFSLK DSMDQTVLGL ALWTGMHTIA AQLLGSGASI NDTMSDGQTL
LHMAIQRQDS KSALFLLEHQ ADINVRTQEG QTALQLAISN QLPLVVDAIC TRGADMSVTN
EKGDPPLWLA LENGLEDIAS TLVRHGCDAT CWSPGPSGCL QTLLHRAVDE NNEVSACFLI
RSGCDVNSPR RPGPNGEGDE EARDGQSPLH LASSWGLEDV VQCLLEFGAN VNAQDSEGRA
PIHAAISNQH NVIIQLLISH PEIRLNLRDR QGMTPFACAM THKNNKAAEA ILKREPGAAE
QVDNKGRNFL HLAVQNSDIE SVLFLISVQA NVNSRVQDAA KLTPLHLAVQ AGSEIIVRNL
LLAGAKVNEL TKHRQTALHL AAQQDQATIC SVLLENGIDF AAEDENGNNA LHLAVMQGRL
NNVRTLLTES NIDAEAFNLR GQSPMHVLGH YGKENAAAIF ELFLECMPEY PLDKPDGEGN
TVLLLAYMKG NANLCRAIVR AGARLGVTNN QGTNIFNYQV ATKQLLFRLL DMLSKEPPWC
DGSNCYECTA KFGVTTRKHH CRHCGRLLCH KCSIKEIPII KFDLNKPVRV CDICFDVLTL
GGVS
//
