ID A0A3P9NXI6_POERE Unreviewed; 1223 AA.
AC A0A3P9NXI6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Tripartite motif containing 33 {ECO:0000313|Ensembl:ENSPREP00000014178.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000014178.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000014178.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000014178.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9NXI6; -.
DR STRING; 8081.ENSPREP00000014178; -.
DR Ensembl; ENSPRET00000014322.1; ENSPREP00000014178.1; ENSPREG00000009576.1.
DR GeneTree; ENSGT00940000156361; -.
DR OMA; ICQNCVM; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000009576; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16766; RING-HC_TIF1gamma; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45915:SF3; E3 UBIQUITIN-PROTEIN LIGASE TRIM33; 1.
DR PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 178..238
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 265..312
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 327..368
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 984..1031
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 1059..1139
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 808..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 397..446
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 18..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..894
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 930..966
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1203..1223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1223 AA; 133373 MW; 5C20C67284687DA9 CRC64;
MRAPGSRTYA GRAAVVRGRK MADNKGEEEM EPSANADPVP SGQAEKQSST ESEDKVIAIE
ADSKGDAETE SPTDANEELN TSSEGVDDSI GGATEATAAT SAAAAVVAAG EADGNASNAA
SPTETSNSNP EPSAGTVDAV PAADAPVGEN TIETSPAPPA PAAAATPVST PINLLDTCAV
CKQSLQTRDC EPKLLPCLHS FCLKCIPQPD RQISVQVPGP HGQTDTHIVN VMRCSVCHQD
YKQSDIIDNY FVKDTTEASS TSDEKAAQVC TSCEDNAGTV GFCVECGEWL CKTCVEAHQR
VKITKDHKIR TKEDADAASD SVNTTGQRPV FCPIHRQEPL KLFCETCDTL TCRDCQLLEH
KEHRYQFLEE AFQNHKGIIE ANMAKLQEKK NYVHYSVSQL QSRLKELGET HRKVEHEIKI
AVFTLINEIN KKGKALLQQL ESVNKERSLR LMGQHKDTTQ LAQQIHHVLN FCNWAITSGS
STALLYSKRP IMYQLRQLFK ARLEPAPQSN GVVRFFCDPT FWAKNVVNLG NLVIEKPPPV
PQPPGVMVGG PTISPGQGHP GKHPGQINLA QLRLQHMQQA AYAQQKHQHQ QHQQQQQQQQ
QQQQQQQIQQ QMRIASQMSH QHPRPGGPPL VQQQPPRLIS MQQLQRTGAM NGGTNPSMYP
SSHHMRLAGP PQGRMPTAQP RLNGQQYAPM MQPQLQRQMS LESEMSHQRF RFLLQSGHSN
PGHAGPFPVA SLHNASPTSP TSASMAGAHA HRGPASPIIG PIELIPSVTN PENLPCLPEI
PPIQLEDAGS SNLGYILSRC ISASQHHQLG STDMNPSPGL STLSPGSSGL SNAHTPARPS
STSSTGSRGS SSSAGRAGTG GGSAAEQLKV KKEPCTEDDY SCSSSVKTER GKDAGRSACM
MSSPESSPLG VPSAGPDAYR DIGERVKTEP MSETSCSGLN GTSSSTSTTT SQTGSVLTNG
SVVKRSGSHD AAQGGGGKDD DPNEDWCAVC INGGDLLCCD RCPKVFHMKC HVPTIKIFPQ
GEFLCTFCRS IAEPEIEYCD ESKRIKGDQS LSPEDQRRCE RLLLYIFCHE LSMGFREPVA
SSVPNYYKII KQPMDLKKVK KKLQLRSSQY YKSKQEFVDD MRLIFKNCAK YNEMSRIIQV
YDEEKEINTQ AGSEMAISGK AVSLYFEEKL QGIFPDQHFP DSPEPGSSDE KEREDVDTED
SEEDFIQPRR KRLKTDDKVV HIK
//
