ID A0A3P9NZS6_POERE Unreviewed; 737 AA.
AC A0A3P9NZS6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Protein 4.1-like {ECO:0000313|Ensembl:ENSPREP00000015070.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000015070.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000015070.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000015070.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017158624.1; XM_017303135.1.
DR AlphaFoldDB; A0A3P9NZS6; -.
DR Ensembl; ENSPRET00000015224.1; ENSPREP00000015070.1; ENSPREG00000010139.1.
DR GeneID; 103460147; -.
DR CTD; 445478; -.
DR GeneTree; ENSGT00940000157047; -.
DR OrthoDB; 5391231at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000010139; Expressed in head.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF17; BAND 4.1-LIKE PROTEIN 2; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 65..360
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 82443 MW; 5217EFC9BF968BE5 CRC64;
MTTEPSEAQP PEAEPFPEAA AHSTPKQGGE GPAHSSLAED SSSPLSSGGL VTRSPARTAL
GFRTMQTRVA LLDGSQFTCM VEKRSRGFQL FEKVCDHLNL LERDYFSLSF RDADSNKNWL
DPAKEIKKQV RGVPWNFSFN VKFYPPNPAQ LSEDITRYFL CLQLRQDVVS GRLPCSFATH
AVLGSYTVQS ELGDYDSDEC APDYVSELCF APNQTKEMEA KIVDLHRTLR GMSPAEAEMH
FLENVKKLSM YGVDLHHAKM TGSRFDCLSA QSEDSEGVAI MLGVCNSGLL VYRDRLRINR
FSWPKILKIS YKRNNFYIKI RPGEFDQFES IIGFKLLNHR AAKRLWKVCV EHHSFFRLLS
PEEPPKKFLS LGSKFRYSGR TQIQSRRASA QISRPAPNFP RCISKRNMLS RSLDGDMGSG
LYGASKAIAV SDHIATVTRR LDDSREEPVE EVLLLLVEEE QKEEERKAAE VSPESPPSPQ
KHDTKTELTD TVVDGDLTVT ESDQDEDLKT QETLGSPEDI VQTSISALRR SFLEGEQGGC
GMTEWDKRLA SSPLRRADDA PMIEPLEPEE PTPSFDEMSP ELTALLKSAR EQETFREHNL
LKTSEKVETV FVLPESGDRD IADHFKEVPV MRKTLTYEAP GSQAGTDPPG GLLLSSQTFT
AETSNTTTTT HITKMVKGGV SETRVEKRIV ISGDTEEDHE QALAAALCEA RRLHPELSVT
RVVVHKETEV PPDHEIN
//
