ID A0A3P9P003_POERE Unreviewed; 450 AA.
AC A0A3P9P003;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Divergent protein kinase domain 1C {ECO:0000313|Ensembl:ENSPREP00000015157.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000015157.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000015157.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000015157.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the DIPK family.
CC {ECO:0000256|ARBA:ARBA00006338}.
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DR RefSeq; XP_008395067.1; XM_008396845.1.
DR RefSeq; XP_008395068.1; XM_008396846.1.
DR AlphaFoldDB; A0A3P9P003; -.
DR STRING; 8081.ENSPREP00000015157; -.
DR Ensembl; ENSPRET00000015313.1; ENSPREP00000015157.1; ENSPREG00000010235.1.
DR GeneID; 103456961; -.
DR KEGG; pret:103456961; -.
DR CTD; 125704; -.
DR GeneTree; ENSGT00390000006452; -.
DR OMA; CGPYYAT; -.
DR OrthoDB; 2968643at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000010235; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR022049; FAM69_kinase_dom.
DR InterPro; IPR029244; FAM69_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR21093:SF2; DIVERGENT PROTEIN KINASE DOMAIN 1C; 1.
DR PANTHER; PTHR21093; UNCHARACTERIZED; 1.
DR Pfam; PF12260; PIP49_C; 1.
DR Pfam; PF14875; PIP49_N; 1.
DR SMART; SM01299; PIP49_N; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..154
FT /note="FAM69 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01299"
SQ SEQUENCE 450 AA; 50908 MW; 2123441D703AFEA2 CRC64;
MLPGAPGGGG AGGRGLLRWL GLRLWSRRGT LLFALLWFGS WLFLNGLVLV HRSIMSDFCT
DDKSRKILQR LCLDFRRGAL SGDLCDDLCV GGLVEYQRCL YYENGKKVME ARWRGNRVIL
KSKLENFSSY EPLGLLDYQE AGEQLSALDV VFYATLEVRN SLGLAEEEEE GGRNGSLWGQ
NLKLREKSYS RADLGSLWAL LQQEEYTFLR VLQDLSPHVA QVLGSCGHFY AVEFLSAGHA
WDQNLFSMDE ASAPRAPGSG GWSSRLMVHQ VALSFMDLVQ HFDNDFTHRL HLCDVKPENF
GIRKDLTVVA IDVDMAFFEP KMRDILEQNC SSDDDCNFFD CWSRCEPGRH RCSPNRRNTN
LQVICEKIFR PWFSPTLLGA KAGLPLQVEL QRAVQDCSET DGGADDEGAA RRVHQRLLAV
LRALLQEEVA PEDRKWTKDE PEHVHTALNF
//
