ID A0A3P9P149_POERE Unreviewed; 583 AA.
AC A0A3P9P149;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Perforin-1-like {ECO:0000313|Ensembl:ENSPREP00000015546.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000015546.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000015546.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000015546.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008414584.1; XM_008416362.2.
DR AlphaFoldDB; A0A3P9P149; -.
DR Ensembl; ENSPRET00000015703.1; ENSPREP00000015546.1; ENSPREG00000010496.1.
DR GeneID; 103468948; -.
DR KEGG; pret:103468948; -.
DR GeneTree; ENSGT00940000164067; -.
DR OMA; LCKNALQ; -.
DR OrthoDB; 4221421at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000010496; Expressed in head.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR46096; PERFORIN-1; 1.
DR PANTHER; PTHR46096:SF3; PERFORIN-1; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00457; MACPF; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51412; MACPF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..583
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018200407"
FT DOMAIN 27..370
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
FT DOMAIN 392..518
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 583 AA; 65553 MW; 31792267A9CBDF09 CRC64;
MFLQSFSIFA GFLLCLPRYS NAACTDGKPR ECQEAEFAPG SNLAGEGFDI TKMERKSAFV
LDMNQWKRKD KTCTLCANPF LEGKKMKLPL SVLDWRAKQT CSAKVSSKLH KSSESLVSSS
TSSVENNWKT ELEVEMKGKS GSLMLAGTNS KVAEYSMEKT KNDKFSFAST SMYCEYYSYR
VSSTPKLNRD FNKAVKKLPK VYSPEYKSRF YTLIDVFGTH YITKVKLGGQ IKSVTSIANC
EASLQGLRTE EIQMCLEAEA SASVKVNVKA ETKHCQTSAE KLDSKKSFSD TFSDRFTEIK
GGLTTDSDLL FSSNKNPDAY KEWLTSVPQY PDLVSYSLSS LHELLPENTP VRKNLRKAIS
HYILEKGLWR NCSERCQAGI RTDSKDSCVC QCHNEPAVNS DCCPTRKGMA RIFITVVKAE
SLWGDHSGGT DGYVKVFLNK EEVYRSSVIV NDNNPKWGAI VDLETRDISS GSVLRFEIWD
EDNKWDDDLL GECERRLSAG VVEDVCPLQH GRFYFKWEVK CIPSLTGSLC TEYNKSRMRE
SLRSLYVSRH AHPIPKSVLV EMGVFVDEGS SHWNQSLAGK TSV
//
