ID   A0A3P9P1A7_POERE        Unreviewed;       579 AA.
AC   A0A3P9P1A7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Perforin-1-like {ECO:0000313|Ensembl:ENSPREP00000015617.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000015617.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000015617.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000015617.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9P1A7; -.
DR   Ensembl; ENSPRET00000015781.1; ENSPREP00000015617.1; ENSPREG00000010513.1.
DR   GeneTree; ENSGT00940000164067; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR46096; PERFORIN-1; 1.
DR   PANTHER; PTHR46096:SF3; PERFORIN-1; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..579
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018231087"
FT   DOMAIN          28..370
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
FT   DOMAIN          388..505
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   579 AA;  64513 MW;  4531DC9A593C85FB CRC64;
     MLLLHVCISA GVLLCLPRCT TGVCTEGTPK QCQEADIAPG TNLAGEGFDI TAMERKGAFV
     LNMDAWRRKN KKCTLCVNPF MENKKQKLPL SVLDWRAKQS CNAKVSSKLH KSSESLVSST
     STSVENNWKV GLEFQTLKTG ASLMLAGTTS KVADYSMEKT KNDKFSFSSL GMSCEYYSYR
     VSNSARLHRE FSKAVNQLPP VYSSESKAQF YKLIDNFGTH YISKVKLGGD VQSITSIRQC
     QASLQGFSAE EVQMCLEVEA SASFRVTVKT ESKHCKKDVE KSESKTAFSS LFSDRFTEIK
     GGHTTEPDLL FSADKDPSAY KEWLKSIPQS PDIISYSLGA LHELLPPKSP TWSNLRSAIS
     HYILEKGLVV NCTERCRKDS RDQCVCQCQN DPAVNQDCCP TRKGMVHLIV TAQRATGLYG
     DYYTSTDGFV KVIYNKKEYR SQVINNNNNP NWNMVVDLGS QDLSVANTVR FEVWDQDNGW
     DDDSLGSCEP RLQNGIKQDV CNMNHGRLYF KLEVKCAPSL TGASCSEYQP TPMNQSLKKL
     YVSRHAQPIP KAMLLEMGVF LNESVSANTS STGRLFHLL
//