ID A0A3P9P4S3_POERE Unreviewed; 1339 AA.
AC A0A3P9P4S3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Roundabout homolog 2-like {ECO:0000313|Ensembl:ENSPREP00000016815.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000016815.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000016815.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000016815.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSPRET00000016995.1; ENSPREP00000016815.1; ENSPREG00000011322.1.
DR GeneTree; ENSGT00940000155457; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000011322; Expressed in head.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR009138; Neural_cell_adh.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF37; ROUNDABOUT GUIDANCE RECEPTOR 3; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 3.
DR PRINTS; PR01838; NCAMFAMILY.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 848..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 126..213
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 218..302
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 307..400
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 411..497
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 518..613
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 632..724
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 729..824
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1217..1236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1261..1278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 146366 MW; 7B2A884B042FD22D CRC64;
MRQTRRDAAS KHVGSRARFE DSAPRIVEDP SDLIVSKGEP ATLNCKAEGR PTPGIEWYKD
GERVETDRDD PRSHRMLLPS GSLFFLRIVH GRRSKPDEGV YTCVARNPLG EAISRNATLE
VAVLRDDFRQ APSDVVVAAG EPAVLECVPP RGHPEPSVFW KRNNARVSSK DDRITMRGGK
LMISPTRKND AGMYVCVGTN MVGERDSDPA ELVVYERPVL VRRPVNQVVM EEETVDFLCE
VHGDPAPTVR WRREEGELPR GRFEIRNGNN LRLFRVKEQD EGTYTCTSEN SVGKTEASAM
LQVHVPPQIT AKPRDQIAAQ GRSITFQCGT TGNPPPAIFW QKEGSQMLLF PGQPPSQSGR
YSVSMSGELI IADVHPEDSG FYVCQAISVA GSVLTKALLE VEGGPSGRIP PIIRQGPANQ
TVSRGAMAQL HCRLVGGTSV KISWEKDGER LQGNKPRVTL MENGTLQIAD LKDTDSGMYT
CVASSPTGES SWSGMLTVRE EGASSGSRAS EFIQLPGPPQ KPVVTEVTKS TVTLTWQSNP
HEGGDAVTSY VIEAFSQSVG STWQTVADHV KHERHTVVGL FPNTVYLFIV RAVNSYGLSD
PSPISEPVRT QDGSPTEQGV DHRQVQRELG EVSIYLQKPV VLSPTSARIS WTVARQSRYI
QGYRVFYRII GGSWLVRDVE ATSDYSVVLA DLQSKKEYEV KIRPYFNELQ GHDSLMVLVR
TPEEVSSGPP QAVSVVQLTN SSSISVSWEP PLHNVQTGII LEYKVWCLSG DAESQINRTV
DGSVLSILLT GLLPDVQYTV AVAAVTSLGV GALSLPVSLL VDQQPVEVKK GGELSMAEQI
ASVIRQPAFI AGLGVAAWLV LMGSGGLLYC RHRRRKQLGH YTTSFAYTPA VGFAHSEGSG
IINGGPGLLG SNMGNYPWLA DSWPTPNLTH SKDFVNCCSG KLDSERYYNS VGIINYPSQT
EKRSTASNDS PIYSTINTAA EDDLLAYYDT YSSVPFNQGP DPYSSNPVLS STGILGLEQD
LDRWTIQSGQ SGSEYAKLQY TKKSNDKLAS QASAGSLSKP APLTWVDVLS LPLPPNKGRD
HPKPDKEEAQ HSSEEEDDDW CPPLPARTYL MDSYREEGSG LPSRPEEVTP SPQHDAPQPS
DSPRVQHFDL LVRHQQSQVS QSNPDLFTNT QALEASDLYN HSSQWADNFR GESLDKGQSL
AVAAESSPTA AAQKPRSKKR APRDGQSRRE RHGDAAELPP PPAPPSADGS LQLFVDVLSR
RQTDNETREG RDLPALLKRG DDSSPQRGGL AKWLSQDENV IPYGQPNVLS KVQTSGYGSL
GGRAFPRPAA AQRRDENLI
//
