ID A0A3P9P5M8_POERE Unreviewed; 1458 AA.
AC A0A3P9P5M8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Neurexin-3a {ECO:0000313|Ensembl:ENSPREP00000017130.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000017130.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000017130.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000017130.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 8081.ENSPREP00000017130; -.
DR Ensembl; ENSPRET00000017312.1; ENSPREP00000017130.1; ENSPREG00000011552.1.
DR GeneTree; ENSGT00940000154618; -.
DR OMA; TDLKFGS; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000011552; Expressed in head.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR15036:SF57; NEUREXIN-3; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1458
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017935544"
FT TRANSMEM 1384..1404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..194
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 190..227
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 250..432
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 439..632
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 636..673
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 678..850
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 864..1039
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1042..1079
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1083..1283
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1294..1329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1427..1458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1441..1458
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1458 AA; 161682 MW; 6841FA7FC8234F80 CRC64;
MDLVGFSIRL QLFLSSCLGL EFLGTPGQWA RYLRWDASTR GDLSFQFKTE ASESLLLYFD
DGGYCDFLQL GVVEGRLQLR FSIDCAETTV VSDRRVDDGS WHAATLSRYN LRTVLVLDGQ
AKADEVKPQR QFMKIVSDLF LGGVPQDIRN GALTLPTVRT MQPFRGTITD LKFGSSQPLF
LGSLKVPLES EGWCTVNPCE NGGTCMVIDG EPVCDCSQTK YKGRFCNEGK KRLQGLTRAA
IMRESREENV ATFRGSEYFC YDLSQNPIQS SSDEITLSFK TWQRNGLILH TGKSADYVNL
ALKDGAVSLV INLGSGAFEA IVEPVNGKFN DNSWHDVKVT RNLRQVTISV DGILTTTGYT
QEDYTMLGSD DFFYVGGSPS TADLPGSPVS NNFMGCLKEV VYKNNDIRLE LSRMARILDP
KMKIQGEVSY KCENVATLDP ISFETPEAYI SLPKWNTKRM GSISFDFRTT EPNGLILFTH
GKRQERKDTA RSQKNTKVDF FAVELLDGSL YLLLDMGSGT IKVKATQTKV NDGAWYHVDI
QRDGRSGTIS VNSRRTPFTA SGESEILDLE GDMYLGGLPV DRSNLILPTE LWTAMLNYGY
VGCIRDLFID GRSKDIRQIA EAQNGAGIKP SCNKQQGKQC ESYPCKNRGV CKEGWNRFIC
DCTGTGYWSR TCEREASILS YDGSMYMKVV MPTVMHTEAE DVSLRFRSQR AYGLLMATTS
QDSADTLRLE LDGSRVKLTV NLDCIRINCN SSKGPETLYA GQKLNDNEWH TVRVVRRGKT
YKLTVDDDVA EGQMVGDHTR LEFHNIETGI MTERRFVSTI PSSFIGHLQS LRFNGMLYID
LCKNGDIDYC ELNARFGVRS IIADPVTFKT KSSYLSLATL QAYTSMHLFF QFKTTSPDGF
ILFNSGDGND FIAVELVKGY IHYVFDLGNG PNLIKGKSER SLNDNQWHNV AITRDNSNTH
TLKVDATATS QTINGAKNLD LKGDLFIAGL GPGMYGNLPK LVASREGFQG CLASMDLNGR
LPDLLNDALF RSGQIERGCE GPSTTCQEDS CANMGICIQQ WENYTCDCSM TSYTGTQCSD
PGTMYIFGKG GGLITFNWPA NERPSTRTDR LTVGFSTSLK DGILVRIDSA PGLGDYLMLH
IEQGKIGVTF NIGTEDITVQ ESSTPVNDLK YHVVRFTRNG GNATLQVDNW SINEHFPTGN
SDIERYQTAN KKIPFKYVRP VEEWLQEKGR QLTIFNTQAT ITVGGSDRGR PFQGQLAGLY
YNGLKVLKMA AEANVNIKIN GSVRLVGNGS SVAGSARTTT MTPELSSNVL ESTTTTTTTT
TRKHRSSTVQ HGAEEIVSSA ECSSDDEDLE ECETIHPALP TEPGVRRVPG PSEVVRESSS
TTGMVIGIVA AAALCILILL YAMYKYRNRD EGSYQVDESR HYITNSAVQS NGAVMKDKQQ
SLKGSNKRQK NKDKEYYV
//
