ID A0A3P9P920_POERE Unreviewed; 871 AA.
AC A0A3P9P920;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Amyloid beta precursor protein binding family A member 1 {ECO:0000313|Ensembl:ENSPREP00000018312.1};
GN Name=APBA1 {ECO:0000313|Ensembl:ENSPREP00000018312.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000018312.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000018312.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000018312.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9P920; -.
DR Ensembl; ENSPRET00000018509.1; ENSPREP00000018312.1; ENSPREG00000012388.1.
DR GeneTree; ENSGT00940000156820; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000012388; Expressed in head and 1 other cell type or tissue.
DR CDD; cd22578; Mint1_CID; 1.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd01208; PTB_X11; 1.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR12345:SF14; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1; 1.
DR PANTHER; PTHR12345; SYNTENIN RELATED; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 505..677
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 690..775
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 781..857
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 101..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 436..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 871 AA; 97671 MW; 6CCBEEDD6A5B6235 CRC64;
MEDMDTRFCH QNMCQNGQHC NLGNQEKCIR CYETSTAESN GGRLRFPDQC RPQKVDMDLQ
TPQPQMTYPV TKSAGRSYCR QGETKAQMKD KWERQILWKQ GDAERSPYTQ QTNSGRGLMP
VNEEQSVLKD QVRTHVPQEK YRKKGNRESA MTEQQHPYPP NDTPSQFLPL TCNLMQDSQD
PERPNETDEM LNADYTSNVY SKPINYSAGQ AICAACENSE NVYTDLYEIY SFSDQVYEEI
CDVPASLFTS FSNENQSLNQ RKISIQQLQS KDRYHYLKKA VGSRLRHYTQ RSDGESDSPE
KDAEFAQYRS TDSCELDEDN EQSVTEVNPP NLGSKAKAKK LSLKDHSEHT TQISSNKNCE
AATQEDSVTH QVLNCSVTET LSIKNSQEKA DAISLVIKDI REAIEEVKTR TIRSPYTPDE
PKEPVWVMRQ DLSSNTEYDF QPCPGDDSPG SGSASPPGAG SSSKLLSQDE SFRGSLSQKE
SRKRLTSFPT YVEVPGPCDP EDLIDGIIFA ANCLGSTQML SEKTPSKNIR MIQAQEAVNR
IKAEPQPITE VDLFISTQRI KVLNADSQET MIDNALRTIS YIADIGNIVV LMARRRLPHC
DSQENVEVSD PSQDSKHQHK MICHVFESED AQLIAQSIGQ AFSVAYQEFL RANGINPEDL
SQTEYSDLMS TQDMYNEDLV HFSRSENCKD VCIEKAKGEI LGVVIVESGW GSILPTVIIA
NMMHAGPAER SGRVNIGDQI MSINGTSLVG LPLSTCQSII KGLKNQSRIK LNIVRCPPVT
TVLIRRPDMR YQLGFSVQNG IICSLMRGGI AERGGVRVGH RIIEINNQSV VATPHEKIVQ
ILSNAVGEIH MKTMPAAMYR LLTAQEQPLY I
//
