ID   A0A3P9PBB3_POERE        Unreviewed;       562 AA.
AC   A0A3P9PBB3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000019102.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000019102.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000019102.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000256|RuleBase:RU361216}.
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DR   STRING; 8081.ENSPREP00000019102; -.
DR   Ensembl; ENSPRET00000019308.1; ENSPREP00000019102.1; ENSPREG00000012428.1.
DR   GeneTree; ENSGT00940000155464; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000012428; Expressed in head.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR   Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR11958:SF63; AMINO ACID TRANSPORTER; 1.
DR   PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361216};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        88..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        126..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        209..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        258..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        298..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
FT   TRANSMEM        331..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361216"
SQ   SEQUENCE   562 AA;  61704 MW;  DA3A86B901E260BD CRC64;
     MSEVELVEVA RPEDNEKNER CSQPLDEVES IRDGFNIWIF LKRNAFLILT MAAVALGIGL
     GFALRYINMS EREITYLTFP GELLLRMLKM MVLPLVVSSI IAGXINFLAF SLAITNNFGK
     IGLRIIIYYL VTTVVATFTG IFLAVFIKPG KSSRHASESS PAKTEDVHSL DAFLDLIRNM
     FPSNLVEACF RKVTTNISTN SESCCYESVI VMILSCHILL ILLLPLLLLY VLLLFDCVDY
     LDCFICCLAP IAGTSDGINV VGLLVFSIAF GLILSSMGSE GKPLRDLFNC MNKAIMRLVS
     IVIWYSPVGI IFLLAGQVVK MTDAAEIGRD VGMYTLTVVT GLIIHGCVTL PLIYVIVTRK
     NPLRFYGGIL QALSTAFGTS SSSATLPVTL RCMEENLKMD KQVTRFMLPV GATMNMDGSA
     LYEAVAALFI AQVNDMDFNF GQIIVLSLVV TAASTGAPGI PQAGMVTMLI VLSSTGLPTE
     DISLLLMVDW ILDRLRTATN VLGDCIGVGV VQHLSRHELQ TSSPTETNLV LEENPPSKSI
     SWPHCTIETR QKKDKIRCAF MW
//