ID A0A3P9PBW3_POERE Unreviewed; 352 AA.
AC A0A3P9PBW3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA repair protein RAD51 homolog 3 {ECO:0000256|ARBA:ARBA00040674};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000019289.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000019289.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000019289.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_008400555.1; XM_008402333.2.
DR AlphaFoldDB; A0A3P9PBW3; -.
DR Ensembl; ENSPRET00000019496.1; ENSPREP00000019289.1; ENSPREG00000013050.1.
DR GeneID; 103460233; -.
DR KEGG; pret:103460233; -.
DR CTD; 5889; -.
DR GeneTree; ENSGT00940000156805; -.
DR OMA; AMETFTV; -.
DR OrthoDB; 1216351at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000013050; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd19492; Rad51C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR PANTHER; PTHR46239:SF1; DNA REPAIR PROTEIN RAD51 HOMOLOG 3; 1.
DR PANTHER; PTHR46239; DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50162; RECA_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 75..262
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT REGION 323..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 38328 MW; 7CA74A83066CB3CD CRC64;
MRRPVSSLSL GSSLKGKLVR AGFQFATDLR DLNPEHLSAE AGVSQQEALE ALQAASSGHG
VAAVTALELL QKEEEFRSIV TFCSQLDEAL GGGVPVGKVT EICGAPGVGK TQLCLQLAVD
VQVPAVFGGL GGQVLFVDTE GGFQVQRLVD LAGAAVRHCS LLAEDEEQRV AMTTFTVETI
LSNVFLVRCR DYVELLAELH LLPDFLPDRP RLRLLVIDSV AFPFLHLHDD LSQRTRLLQG
LGLRLIAAAT DHNIAVVTTN HMTTRLRGSQ AQLVPALGDL WGHAPSIRLL LRWEESRRLA
SIVKSPGHMD ATVQYQITCQ GFRDADQSEQ PQSKRPRTQT DQSASSRENT RT
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