ID A0A3P9PC88_POERE Unreviewed; 792 AA.
AC A0A3P9PC88;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Polyhomeotic homolog 2 {ECO:0000313|Ensembl:ENSPREP00000019422.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000019422.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000019422.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000019422.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3P9PC88; -.
DR STRING; 8081.ENSPREP00000019422; -.
DR Ensembl; ENSPRET00000019630.1; ENSPREP00000019422.1; ENSPREG00000013115.1.
DR GeneTree; ENSGT00940000154964; -.
DR OMA; HSPAHET; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000013115; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF86; POLYHOMEOTIC-LIKE PROTEIN 2; 1.
DR Pfam; PF16616; PHC2_SAM_assoc; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 600..634
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 728..792
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 502..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 84055 MW; 1424A26862DF6E85 CRC64;
MESEPGAPAS TTGSTGTVST TSSSSTSTPA TTSSSSSAVA VSTSASTSTT TASTTSGSSN
SVSSSSNSSG SIPSSSSSNS TSVFQQALHR QPNTAAQYLQ QMYAAQQQHL MLQTAALQQH
SLSTAQLQSL AAVQQASIAA GRQSSSQNGT SSQQTGSTQA TINLTTSPAA AQLISRAQNI
SSTPTSISQQ AVLLGSQSTL TPSQAQMYLR QQMAQQSNLV QVARSLSRAV PLSPQLIFTP
AATVTAVQSE SATQASSQNQ VQNLAIRGQQ GATTSSSQTQ TLPLSLKQNP VPIQPASLIK
NPSQGTQTSS GLKSSSSDSP PDGGKKGDGQ AVTEVRAINM SRSITAVSAQ PLIAPAYTQI
QPHSLVQQHK QQQQFVVQQT QGSQRTTGQL LQTASIQPSQ HPVPVLPKPA PHQPSAPSQQ
ATIFHSTLSS HALHSPLNQA KAQPVQLTAI NLQIQPAVCN FVESNLKHKH FSAISPKTWN
VSFSRSGGGS AKRPVTTPGT PPPAMTSGNE SEAPTVTGSA PQNGENKPPQ AIVKPQVLTH
VIEGFVIQEG AEPFPVERLP ILIDSPKKLD HQLSSDPDKT PVSNAANTDS DFTYAAYFCT
EKEEPKLTCE YCGWVDFAYT FKGSKRFCSV VCAKRYNVGC TKRVGLFRPE KNKTTNRWRK
RPHSRSSIEA KKQLSIQKSF SSISSPHASQ PSQEESSPCS DISGPQACAG RDAALLNERF
LPNDPAKWNV EEVYEFIRSL PGCQEIADEF RSQEIDGQAL LLLKEDHLMS TMNIKLGPAL
KIFARINMLK DS
//
