ID   A0A3P9PE22_POERE        Unreviewed;       463 AA.
AC   A0A3P9PE22;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Sorting nexin 7 {ECO:0000313|Ensembl:ENSPREP00000019923.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000019923.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000019923.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000019923.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   AlphaFoldDB; A0A3P9PE22; -.
DR   STRING; 8081.ENSPREP00000019923; -.
DR   Ensembl; ENSPRET00000020136.1; ENSPREP00000019923.1; ENSPREG00000013493.1.
DR   GeneTree; ENSGT00940000155315; -.
DR   OMA; LHYYEEC; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000013493; Expressed in caudal fin and 1 other cell type or tissue.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR   PANTHER; PTHR45949:SF3; SORTING NEXIN-7; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   DOMAIN          65..185
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   COILED          314..362
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   463 AA;  53510 MW;  45A4E2F209BD7757 CRC64;
     MSGATVPADI SGHMLDLDED EDLEVFSKNT SLADGNPMPN SPDSMVNQFR LDEENEEEQQ
     GAINKDIFVT VDNPESHISA IETFITYRVV TRTTCSEFDS SEYEVRRRYQ DFLWLKSRLE
     ENYPTLIIHP LPEKFVMKSM VERFNDDFIE TRRKALHRFL NRIAEHPILS CSHHFKVFLT
     EEELAPHRKL GPGFLSRMSD TMRAMANSVR GLRSKLEEFA VMQEYVDDFS NKMCSVDKVT
     HRIIKEHREY MDELKQYGPT YFQWAESEEL LAEPLKGVGS CVERCSKETE EQIQHLSEFL
     VPTLHEYVLC ADTLKAVMRR RDNIQAEFEA KNEALASRTT DKEMLQEEVD DLADRVEQAN
     NALRGDWSRW RTSMRADLKS AFISTAAKNV DYYEKEGGDG HANDKTCDDI RPMVAVFRHT
     VQASEEGETH EPQRHDGLSQ ARPLGLDRAG HIHLPEETHD RVR
//