ID   A0A3P9PED1_POERE        Unreviewed;       411 AA.
AC   A0A3P9PED1;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Aminopeptidase like 1 {ECO:0000313|Ensembl:ENSPREP00000020261.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000020261.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000020261.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000020261.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
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DR   AlphaFoldDB; A0A3P9PED1; -.
DR   STRING; 8081.ENSPREP00000020261; -.
DR   Ensembl; ENSPRET00000020475.1; ENSPREP00000020261.1; ENSPREG00000013703.1.
DR   GeneTree; ENSGT00530000063255; -.
DR   OMA; MVCEQSD; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000013703; Expressed in head and 1 other cell type or tissue.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00433; Peptidase_M17; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   Gene3D; 3.40.50.10590; Zn-dependent exopeptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   PANTHER; PTHR11963:SF4; AMINOPEPTIDASE NPEPL1-RELATED; 1.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT   DOMAIN          228..235
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
FT   REGION          387..411
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        397..411
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   411 AA;  43590 MW;  07F72F266482930D CRC64;
     VVCERSDVFA SACAVARAFP LFTRRSASSR RTEKKHVTVE FVVVNNDGGL LDDAELKCLS
     NAADGVRLAA RIVDTPCSEM NTDHFLDEIK VVGSELGITP VIIRGEELKQ RGFGGIYGVG
     KAAEHPPALA VLSHTPDGAT QTIAWVGKGI VYDTGGLSIK GKTTMPGMKR DCGGAAAILG
     AFKATIKQGF KDNLHAVFCL AENSVGPTAT RPDDIHTLYS GKTVEINNTD AEGRLVLADG
     VVYASKDLSA DIILDMATLT GAQGISTGKY HAAVMTNSEQ WEGACVRAGR SSGDLAHPLV
     YCPELHFSEF TSAVADMKNS VADRENAQSS CAGLFIGSHL GFDWPGVWVH VDIASPVHAG
     ERATGFGVAL LMALFGQASD DSMLNQVSPL GAPTNKPEDQ MERDCKRRRL V
//