ID A0A3P9PFL5_POERE Unreviewed; 1461 AA.
AC A0A3P9PFL5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Macrophage mannose receptor 1-like {ECO:0000313|Ensembl:ENSPREP00000020701.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000020701.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000020701.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000020701.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR RefSeq; XP_008432795.1; XM_008434573.2.
DR STRING; 8081.ENSPREP00000020701; -.
DR Ensembl; ENSPRET00000020921.1; ENSPREP00000020701.1; ENSPREG00000014004.1.
DR GeneID; 103479889; -.
DR KEGG; pret:103479889; -.
DR GeneTree; ENSGT01050000244842; -.
DR OMA; ICYSKGV; -.
DR OrthoDB; 4271106at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014004; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 7.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 8.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803:SF124; C-TYPE LECTIN DOMAIN FAMILY 19 MEMBER A-RELATED; 1.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 8.
DR SMART; SM00034; CLECT; 8.
DR SMART; SM00059; FN2; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 8.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 3.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 8.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1461
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018166988"
FT TRANSMEM 1385..1407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..197
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 208..327
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 351..467
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 492..607
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 640..758
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 786..900
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 928..1070
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1091..1202
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1249..1360
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 760..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1461 AA; 164957 MW; 2B7167779E1E1DA0 CRC64;
MRSTCIVTVL LLKMLQCLAL DDSPFQLTNA AGFCLVKTDS VCQEIRWTTA DRLLVPGKNK
CLGVQGTTPM SEVSLYDCDE NNELQKWNCT KDYLLTLQAS TGQKLFVELH ADNRAVLVTT
AGPISKLVIS GTSSGACTRT YREFYTIGGN AAGRPCMFPF FYENQWYSSC TLADSRNQHW
CSVETKYEHQ TWGYCPTNNK DSWIKHPTSG ALYQLNTESA LTWSEAETSC KQQSASLLTI
TDPQEKAYIT ALLEPGGTHQ GYKLWTGLTL DSEHGWQWSN GDPFRYLNWD SGHPVNNPAH
TCGVVDGNVR YAWQSSTCNK KFGYICYSKG VLAAPTAGPD MGHCSAPWVP YNGHCFRLYR
NAQSWSXAQQ TCRKEGGDLA SIRNTEDHSF ISTELGYAST DELWIGLNDK KTEGLFDWTD
HTTVTFTSWQ FGKPQGGNNQ NDCVLVRGEN GNWADDDCTK SHGFICMKAS ASEPTGDEVQ
QDAGCKTGWK RYGSYCYFIG TERKTFGDAK EDCKRSNSYL ADVSNRVDNA FLVSLVGLRS
EKHFWLGLSN QKNRDVFEWT STAPVRYTHW NREMPGHNQG CVAMTTGSTA GLWDVLPCTS
REKYICKYQA EGTAQTPAPT TAPSALCAKG WTRVQSRYVC HKVFSESKSW FEARDYCRGI
GGDLMSVHSA AEINFNMETP RYYYSRSSAL WIGLSANDQG TGYEWSDGSP VNFQHWQDGE
PNNKNNVESC VEFTSRNFDD SGSWNDNQCE ARNGFVCQIR TGLTPQSPPP TPTPDYNRTD
DGWLEWGGNK YYFENRQMAN EDARKSCREK HADLVTINSE AERIFLWKQI SRRSSSFWIG
LTVDLDKSFQ WMDGSPVIYQ MWDEGQPNFA NNDENCVSMR SFHGFWHDYN CGFEFGSICK
RSSSPPVNAT VAPTAPPKGN CKDGWQKINS KCYKIISDKT LTWLDARQQC IDMEGNLASI
PSRHEQVFLV SEMSKTPNRD LWIGFQSSYG NGFYWTDGRP RSYVNLESER RIYHFPHLSH
RYGPMYDHDD DIFVSLRNEK RCAVINANPS FGIGKWIPKS CNDTNGFICS MPLNDKLPNK
TQTNPENYFK ILNDSIKLVT QQKNWSEAQK ACEADGAKLV SVRTEWTQAY IELLALNLNR
SLWIGLNKKQ TNNYFRYVEG WPLIFTRWSG NEPRRDGICV YVDVDGKWKT NDCNQEFSSL
CMKSTDIPPE VKADDYPGVC PEDPHLSMSG YRPSRFSFGQ RQWQAWKPFR GFCYLFSSDE
KEWQDATTSC LGHGGSLASI GDPFEQEFIL NSIKSFQDSH TSYWMGLYKT NKGEWKWLDN
MVMDFENWQN YPSGPFGMIS ASDGKWHTGQ RWMDRPYICK AAKVLLSKPS SAPSVVSGPQ
GRGHAALTAV LVIAGIAAGA GVAFFLFKKS GRQMMTRPIP GGLTAFDNPL FSSNRTQKNL
VDTKKLLGNA DEDNSQPVIT I
//
