ID   A0A3P9PFR5_POERE        Unreviewed;      1013 AA.
AC   A0A3P9PFR5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=GTF2I repeat domain containing 1 {ECO:0000313|Ensembl:ENSPREP00000020523.1};
GN   Name=GTF2IRD1 {ECO:0000313|Ensembl:ENSPREP00000020523.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000020523.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000020523.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000020523.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P9PFR5; -.
DR   STRING; 8081.ENSPREP00000020523; -.
DR   Ensembl; ENSPRET00000020737.1; ENSPREP00000020523.1; ENSPREG00000013881.1.
DR   GeneTree; ENSGT00940000159414; -.
DR   OMA; VFDVLYX; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000013881; Expressed in head and 1 other cell type or tissue.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 5.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 5.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 5.
DR   PROSITE; PS51139; GTF2I; 5.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          102..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          485..533
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          548..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          955..976
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        552..569
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        573..589
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  110994 MW;  E025844AEB9BA564 CRC64;
     MAQMRKLACD GLRASSRGEP QVQLLSARQE ILTSLVSALD SVCMAMSKLN AEVACVTVHE
     DSVIAVGTEK GRMFLNSRRE IQTDFYKFCR APCLQSLTAV NTHTKDQEGD PIKLSKDGEH
     AKQRAPSDPQ SNVFVLRKMV EEVFTVLYSE ALGKSSLVPV PYEWIQKDPG YVVAHGLPEG
     VVLKKPSEYD TKTLMKILEH SHRIHFTAKR QAEDLSREAK PSTEVNNNPS AAAAVVTPSS
     HGAAKAVTSP SPATANNSVL SNFLYGMPMS SKPHPDSKLD FKPATLLNLG KDRLANWTEK
     GSTGKDIGNT DEPTRLPAEQ GQSPPGIHIS KRLLFSIVHE KSEKWDLFIR ETEDINTLRE
     CVQILFNSRY AEALGLDHMV PVPYRKIACD PGAVEIIGIP DQIPFKRPCT YGVPKLKRIL
     DERHGIRFII KRMFDERIFT AAGKIAREEG KLDPGCAPED GFSDCLGFPP TAAELLSNAH
     SSRSTSACVS PQADSEAGPS GDGAPLRRIK TEPPDGDIIQ VTVPDAGTSG EDPVECLGEA
     VSAALCPTTA SPSAPPAAPA PPVPPAPLHP KENQSAEASS PSGAPQSIRR PTEAGSLVED
     IGEMILQLRR QVENLFSIKY AEALGLPEPA KVPYSKFQMY PEDLYVTGLP EGISLRRPNC
     FGAAKLRKIL AVSSQIQFFI KRPELLAEQV KQEMPSMPVC DAGMFQLELQ ILSEPDAKDS
     TPAEDTAALS KRPGFSECME SKLSRIDLAN TLREQVQDLF NRKYGEALGI KYPVQVPYKR
     IKNNPDSVII EGLPPGIPFR KPCTFGSQNL ERILAVADKI SFTITRPFQG LIPKPAPRRV
     TLLKKAYASI SDDDDINRMG EKVVLREQVK ELFNKKYGEA LGLDRSVVVP YKLIRGSPES
     VEVGGLPDDV PFRNPNTYDI VCLEKILQAA DKVTFNIKSQ LQPFAEICSQ ACNTAGTDAS
     TNRRKRKRVQ ESSRIPASSD LGISANQIPV MQWPMYMVDY SGVNVQVPGK VNY
//