ID A0A3P9PHP7_POERE Unreviewed; 351 AA.
AC A0A3P9PHP7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Heparan sulfate 2-O-sulfotransferase 1-like {ECO:0000313|Ensembl:ENSPREP00000021314.1};
GN Name=HS2ST1 {ECO:0000313|Ensembl:ENSPREP00000021314.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000021314.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000021314.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000021314.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010569}.
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DR RefSeq; XP_008405967.1; XM_008407745.2.
DR AlphaFoldDB; A0A3P9PHP7; -.
DR STRING; 8081.ENSPREP00000021314; -.
DR Ensembl; ENSPRET00000021539.1; ENSPREP00000021314.1; ENSPREG00000014411.1.
DR GeneID; 103463968; -.
DR KEGG; pret:103463968; -.
DR CTD; 100151174; -.
DR GeneTree; ENSGT00530000063408; -.
DR OMA; TTWREMK; -.
DR OrthoDB; 5401406at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014411; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12129:SF13; HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 ISOFORM X1; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT COILED 24..51
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 351 AA; 40924 MW; 442A22E949F4F493 CRC64;
MGLLRSTMPP KIQLLAVLAF GVAMLLIENQ IQRLDESRAK LERTMARHEV VGVELRRSED
GGGREADDSV IIYNRVPKTA STSFTNIAYD LCSRNRFHVL HINTTKNNPV MSLQDQVRFV
RNVTTWREMK PGFYHGHVAY LDFSKYGVKS KPMYINVVRD PIERLVSYYY FLRFGDDYRP
GLRRRKQGDK KTFDECVSSG GSDCAPEKLW LQIPFFCGHH SECWNAGSRW ALEQAKYNLV
NEYLLVGVTE ELEDFIMILE AVLPRFFKGA TELYRSGKKS HLRKTTEKKP PTKETIAKLQ
QSDIWKIENE FYEFALEHFQ FVRAHTVREK DGELYVLAQS FFYEKIYPKL S
//
