ID A0A3P9PHW9_POERE Unreviewed; 467 AA.
AC A0A3P9PHW9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Peripherin {ECO:0000313|Ensembl:ENSPREP00000021288.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000021288.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000021288.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000021288.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_008408228.2; XM_008410006.2.
DR AlphaFoldDB; A0A3P9PHW9; -.
DR STRING; 8081.ENSPREP00000021288; -.
DR Ensembl; ENSPRET00000021513.1; ENSPREP00000021288.1; ENSPREG00000014389.1.
DR GeneID; 103465318; -.
DR KEGG; pret:103465318; -.
DR CTD; 5630; -.
DR GeneTree; ENSGT00940000160203; -.
DR OMA; THSRKMV; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014389; Expressed in head.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF14; PERIPHERIN; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 93..406
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 26..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 83..117
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 141..238
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 304..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 47..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 53959 MW; 48C84F5D5BF5B26C CRC64;
MSHSSVTSTS YRRTFGSPHP ISLSSYSPVS SRLPMSGGRY GRSASPAVAA RSTTYHQQRS
RPAPQVQRLS YDKVDFTLAE AINQEFLATR SNEKAELQEL NDRFASFIEK VRYLEQQNGA
LTQELNQFKG QYQHGQPNRA SELFQEELRE LRRQLDAVGK ERDQYQLERD NLAEDLSLIK
QRLDEEAQKR ADAESNLVAF RKDVDDATLS RLELERKIES LMDEIEFLKK LHDEEIQDVQ
VSVQTHQLKM EVDNSSRPDL TGALRDIRAQ YETIAMKNMQ ESEEWYKSKF ADLTESAKRN
TDALRQAKQD ASESRRQIQA LNCETDALKN TNEALLRQMR EMEDQFGVEI GNYQDNVGRL
EDEIRHLKEE MARHLREYQD LLNVKMALDI EIATYRKLLE GEESRISIPI LNVGMSNHFG
DRDYERAPDT HGKKTVVIKT VETRDGEVVK ESRREKESDS GKTDKDE
//
