ID A0A3P9PI17_POERE Unreviewed; 1325 AA.
AC A0A3P9PI17;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Mitogen-activated protein kinase 8 interacting protein 3 {ECO:0000313|Ensembl:ENSPREP00000021395.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000021395.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000021395.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000021395.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the JIP scaffold family.
CC {ECO:0000256|ARBA:ARBA00009866}.
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DR STRING; 8081.ENSPREP00000021395; -.
DR Ensembl; ENSPRET00000021619.1; ENSPREP00000021395.1; ENSPREG00000014230.1.
DR GeneTree; ENSGT00940000153496; -.
DR OMA; MRNVSIX; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014230; Expressed in head.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF3; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 6..94
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 491..562
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 179..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1281..1311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..161
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 179..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..682
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..757
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..906
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..953
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1325 AA; 146957 MW; 1B899825C4E52DD3 CRC64;
MMEIDEVVYQ DDYGSGTVMS ERVSGLANSI YREFERLIHS YDEEVVKELM PLVVNVLENL
DAVLTENQEH EVELELLKED NEQLITQYER EKALRKQAEE KFIEFEDSLE ADKKELQIQV
ELLELQGKQL ELKTKNYSDQ ITRLEEREAE MKKEYNALHQ RHTEMIQTYV EHIERTKLQQ
AGSNSQSEGP GCGRTQRHTW RKSKAERPPS LSLYPGGEGM VRGGHGGARM MPGKDIWQED
ESESDSVAAT PSSTGSKSNT PTSSVPSATV TPINEGFPPH YDFDMMRTGN RRKGAKRLSR
NMEVQVSQET RNVSIGMGSS DEWSEFQEII DSTPELEMGM DSRVYGGGNS PSQGIVNEAF
GINTDSLYHE IKDAKSDIIG DVDAGAELLG MGKEVENLLT ENKQLLETKN ALNIVKNDLI
AKVDELSSEQ EVLKEELEAV RQSKNKVDAR IKELEEEIKR LRAEASRDSK DEVGDDFSSP
MQDGDMSMTQ RRRFTRVEMA RVLMERNQYK ERLMELQEAV RWTEMIRASR ESPPIQEKKK
STIWQFFARL FSSSSSPPPV KRPYSSVNIH YKSPSPAFNQ RRSHTMCQIS TSNRTLEFFP
EELASNGVAS LLSDSALMAR REQRREQYRQ VREHMRRDDG IMQACGWSVP SRLKQTGGQT
DGAKDSPLKR QQTNEKEDNR MKNVPVPVYC RPLVEKDPNR KLWCAAGVDL TGWRVSSQEV
APPKAPPGSG DPLQTEEDRV DKKNTSPEKR KSKDLQETDS MNSRVWILTS THSASKVVII
DANQPGSLVD QFNVCNAHVL CISSVPAASE SDYPAGEIVL DPGDGGAGGG DDMGGVEGML
AGITLVGCAT NCSVARSNCS SRTDTPIVDK GQAPAAPPTN GKIHPAQSTE EATEATEVSE
STASHAEMGS GRPGPFTEHV FTDPQPRPAD DRSAGQSKEE SSQPTESEEG GEETKNYTSV
APTMWLGAQN GWLYVHSAVG NWKKCLHSIK LKDSVLSLVH VKGRVLVALA DGTLAIFHRS
EDGLWDLSNY HLMDLGRPHH SIRCMAVVHD KVWCGYKNKI HVIQPKSMQI EKSFDAHPRR
ESQVRQLAWI GDGVWVSIRL DSTLRLYHAH THQHLQDVDI EPYVSKMLGT GKLGFSFVRI
TALLIGGNRL WVGTGNGVII SIPLTETVVL HRGQLLGLRA NKVSPTSSGG VIHVYGDDSS
EKSTGSFIPY CSMAQAQLCF HGHRDAVKFF VSVPGNVLAT LNGSVLDSPS EGQSTAAPTE
TEAQSVQNVL VLSGGEGYID FRIGDGEDDE TEEGDSGGGA SQMKPALSKA ERSHIIVWQV
SYVPE
//
