ID A0A3P9PIT4_POERE Unreviewed; 124 AA.
AC A0A3P9PIT4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 {ECO:0000256|ARBA:ARBA00018681};
DE AltName: Full=Complex I-B15 {ECO:0000256|ARBA:ARBA00030212};
DE AltName: Full=NADH-ubiquinone oxidoreductase B15 subunit {ECO:0000256|ARBA:ARBA00030987};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000021618.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000021618.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000021618.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004298}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004298}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004298}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB4 subunit family.
CC {ECO:0000256|ARBA:ARBA00007260}.
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DR AlphaFoldDB; A0A3P9PIT4; -.
DR STRING; 8081.ENSPREP00000021618; -.
DR Ensembl; ENSPRET00000021843.1; ENSPREP00000021618.1; ENSPREG00000014620.1.
DR GeneTree; ENSGT00390000007133; -.
DR OMA; REYLLHY; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014620; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009866; NADH_UbQ_OxRdtase_NDUFB4_su.
DR PANTHER; PTHR15469:SF0; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4; 1.
DR PANTHER; PTHR15469; NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT; 1.
DR Pfam; PF07225; NDUF_B4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 124 AA; 14620 MW; FD31BD6C791A1274 CRC64;
MADYREAPLA TRPKTLDPNE YFNLSPDYRR AEEERAALRA NLKRQYQLQL NNPHRTELIE
DPALTRWVYA RANPYPHFRP TKKTSLLGVM FGVVPLFRPL CLLFALCFTD KFNHGPTCLM
FIRY
//
