ID A0A3P9PJM6_POERE Unreviewed; 438 AA.
AC A0A3P9PJM6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cell adhesion molecule 2 {ECO:0000313|Ensembl:ENSPREP00000022081.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000022081.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000022081.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000022081.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR RefSeq; XP_008425393.1; XM_008427171.2.
DR Ensembl; ENSPRET00000022273.1; ENSPREP00000022041.1; ENSPREG00000014893.1.
DR Ensembl; ENSPRET00000022312.1; ENSPREP00000022081.1; ENSPREG00000014893.1.
DR GeneID; 103475503; -.
DR KEGG; pret:103475503; -.
DR CTD; 793954; -.
DR GeneTree; ENSGT00940000155947; -.
DR OrthoDB; 3039994at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000014893; Expressed in head.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003006; Ig/MHC_CS.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR45889:SF1; CELL ADHESION MOLECULE 2; 1.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS00290; IG_MHC; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..438
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040681133"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..128
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 136..228
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 233..318
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 438 AA; 47774 MW; 16AAD860279B1AF0 CRC64;
MNLKSNLIFT LYTIYGILLK VMASKGKVRG ISGQYPLVQN VTVTEGGTAN LTCRVEYNDN
TSLQWSNPAQ QTLFFGDKKA LRDNRIELVR ATSSELTISI SDVTLGDEGL YTCSLFTMPV
RTAKAYLTVL GVPEKPEING LTKPAMEGDH ITLTCITQGS KPAADLRWFR NEKEVKGAKE
VNASGKTFTV RSSLQLHVDR NDDGVAYTCR VDHVALAQAP QQATEVLEVH YAPRVEIIKS
TTVPQEGQYL KLECFSRGNP SPDPVMWTKD GGDLPDLDRI IVEGRELTFT SLNKTDNGTY
RCEASNHLGT SSAEYVLYVY DAPTTLPPST TPPLHPILPD PTVQLSTHAS DPTVTGSRDP
NALGQHGTDH ALIGGVVAVV VFVTLCLIIV LGRYLARHKG TYLTNEAKGA DDAPDADTAI
INAEGNHAHA EEKKEYFI
//
