ID A0A3P9PLA5_POERE Unreviewed; 463 AA.
AC A0A3P9PLA5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Inositol polyphosphate 5-phosphatase K-like {ECO:0000313|Ensembl:ENSPREP00000022515.1};
GN Name=INPP5K {ECO:0000313|Ensembl:ENSPREP00000022515.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000022515.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000022515.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000022515.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR AlphaFoldDB; A0A3P9PLA5; -.
DR Ensembl; ENSPRET00000022752.1; ENSPREP00000022515.1; ENSPREG00000015210.1.
DR GeneTree; ENSGT00940000156538; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000015210; Expressed in head.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR CDD; cd09094; INPP5c_INPP5J-like; 1.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF117; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF17751; SKICH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 12..337
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT REGION 278..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 53254 MW; 8AB1BB3C9DA92971 CRC64;
MSTERFTSGW TDKYRLHMVT WNVATAEPPE DVASLLQLND QPAIDLYVIG LQEVNATPVR
FLSDLMAEDS WSHLFMDTLG PKGFVKVTSV RMQGLLLLVF AKMMHLPFIR NIQTTYTRTG
IFGYWGNKGA VSVRFSFYGH MMCFLNCHLA AHMHNALQRV DEFEYILETQ DFDIFDTPHV
LDHKVVFWFG DLNFRIEDHG LHFVRSSING GRLNLLWSKD QLTMMKKKEP FLQEFDEGPL
NFKPTYKFDR KAESYDTSGK KRKPAWTDRI LWRIKPKSLP SEEDDDDDEK ASTPADDGQE
EYPIMVTQNT YTSVMSYGVS DHKPVIGNFT LELRKYFDTQ LVDLAPAGEW SADHDALLSY
TILEDFMSST WDWIGLYKVG FKSASDYKTF VWVRENELPE VNEVIEKSVV KDDLPLLSGE
YVLGYYSTNL NSIVGLSDNF QILESKRAAM EGLVSKDING IDK
//
