ID A0A3P9PNG6_POERE Unreviewed; 619 AA.
AC A0A3P9PNG6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=X-ray repair cross complementing 1 {ECO:0000313|Ensembl:ENSPREP00000023427.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000023427.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000023427.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000023427.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_008429435.1; XM_008431213.2.
DR RefSeq; XP_008429436.1; XM_008431214.2.
DR AlphaFoldDB; A0A3P9PNG6; -.
DR STRING; 8081.ENSPREP00000023427; -.
DR Ensembl; ENSPRET00000023667.1; ENSPREP00000023427.1; ENSPREG00000015808.1.
DR GeneID; 103477880; -.
DR KEGG; pret:103477880; -.
DR CTD; 7515; -.
DR GeneTree; ENSGT00390000004140; -.
DR OMA; PEWIYAI; -.
DR OrthoDB; 1334125at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000015808; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
DR GO; GO:0000012; P:single strand break repair; IEA:InterPro.
DR CDD; cd17725; BRCT_XRCC1_rpt1; 1.
DR CDD; cd17707; BRCT_XRCC1_rpt2; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR045080; BRCT_XRCC1_rpt1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002706; Xrcc1_N.
DR PANTHER; PTHR11370:SF6; DNA REPAIR PROTEIN XRCC1; 1.
DR PANTHER; PTHR11370; DNA-REPAIR PROTEIN XRCC1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF01834; XRCC1_N; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50172; BRCT; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT DOMAIN 328..416
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 526..617
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 171..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 463..485
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 68657 MW; 80619ABA5A04FD88 CRC64;
MPEIPLKHVI SCSTEDSTHK ANNLLSSDTY RKWKASKPGE KQTSVILQFE KEEQVHSIDI
GNEGSAFIEV LVGNSSAVKD QDYEVLLVTS SFMSPTESRN GTNMNRVRFF GPNQLQKSTA
QEKWDRVKIV CSQPYSKNIA YGLAFVKFHS PPDKTDPPTS SPKLTKLGQF RVKDESPSSG
PSLQPGSLFF NRDNATKPST SLKVSPQSDK LSYAAAALQA GGSTQSPGQA STSISASPQP
PAKRKFEFSK ERQSPSGPPP TKKMSPGGSP ETKAATPKYK PSPVSTPSPS TAKASSAKKS
AEKKKESQSK PEPKPKPKTK SQSEQQAPFN RLMEGVVFVL SGFQNPFRGE LREKALEMGA
KYRPDWTPDS THLICAFANT PKYSQVKSAG GIIVRKEWVM DCHKRKQKIS HKRYLMDGAE
SSSESETDGD DQSEEETKTP QKQAKQVTPK KTPEKKDEDD EYGGSTDVDE PAGGDEDDES
GVDTEDELQR VESKQKKAAV KEEDPYGGST DENTDAEAEE DHPIPELPDF LHGKHFFLYG
KFPNNERRLL LRYIVAFNGV IEEYMSDKVQ FVVTSGGWHE SFEDALMENC NLNFVKPAWI
YAINERQKML PYQPYTVVP
//
