ID A0A3P9PXL6_POERE Unreviewed; 253 AA.
AC A0A3P9PXL6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Patatin like phospholipase domain containing 4 {ECO:0000313|Ensembl:ENSPREP00000026631.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000026631.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000026631.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000026631.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008428437.1; XM_008430215.2.
DR RefSeq; XP_008428484.1; XM_008430262.2.
DR AlphaFoldDB; A0A3P9PXL6; -.
DR STRING; 8081.ENSPREP00000026631; -.
DR Ensembl; ENSPRET00000026911.1; ENSPREP00000026631.1; ENSPREG00000018013.1.
DR GeneID; 103477238; -.
DR KEGG; pret:103477238; -.
DR CTD; 8228; -.
DR GeneTree; ENSGT00940000165158; -.
DR OMA; KGEKWID; -.
DR OrthoDB; 5395310at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000018013; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050253; F:retinyl-palmitate esterase activity; IEA:InterPro.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07222; Pat_PNPLA4; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR033562; PLPL.
DR InterPro; IPR033902; PNPLA4.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR12406; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED; 1.
DR PANTHER; PTHR12406:SF7; PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..176
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 253 AA; 27820 MW; BA0E6CFB851A61B3 CRC64;
MTIVNLSFAA CGFMGIYHLG AVGAFLRHGD KLLGSLRACA GASGGALMAA VLITAPDKLE
HCTEFTYKFA ESVRQQRFGA ITPGFNFMLI LREALEEILP SEAHSLASDR LYVSITHCRS
GKNHIVSRFP SRDELIMALL ASSFVPLYAG LRPVEFSGQK WIDGGFTDSL PILPVGRTIT
VSPFAGLQDV CPVHRGRFNT QLSIANMKVM FSMENIKRLN QALFPPSLRT MHAICEEGHT
DAVRFLKRED LMS
//
