ID A0A3P9Q0R4_POERE Unreviewed; 498 AA.
AC A0A3P9Q0R4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Endoplasmic reticulum protein 44 {ECO:0000313|Ensembl:ENSPREP00000027645.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000027645.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000027645.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000027645.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P9Q0R4; -.
DR STRING; 8081.ENSPREP00000027645; -.
DR Ensembl; ENSPRET00000027946.1; ENSPREP00000027645.1; ENSPREG00000018712.1.
DR GeneTree; ENSGT00930000151031; -.
DR OMA; LFYRDEC; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000018712; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0007507; P:heart development; IEA:Ensembl.
DR GO; GO:0010882; P:regulation of cardiac muscle contraction by calcium ion signaling; IEA:Ensembl.
DR CDD; cd02996; PDI_a_ERp44; 1.
DR CDD; cd03072; PDI_b'_ERp44; 1.
DR CDD; cd03070; PDI_b_ERp44; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 3.
DR InterPro; IPR041862; ERp44_PDI_b.
DR InterPro; IPR041870; ERp44_PDI_b.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46295; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44; 1.
DR PANTHER; PTHR46295:SF1; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 3.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..498
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018245533"
FT DOMAIN 20..142
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 412..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 56584 MW; D10AED0B18BF30B7 CRC64;
MKLFAISPSL DIRFAAVILL VMGLSTPGKA EIISLDSSNI DDVLNNAGVA LVNFYADWCR
FSQMLHPIFE EASNIVREEF PDTKQVVFAR VDCDQHSDIA QRYRITKYPT LKLFRNGMMM
KREYRGQRSV TAIADFIRQQ QVDPVKEIHS MEEVNTIDRS KRNIIGYFEQ KDSDNYHTYE
KVANILRDDC TFSAAFGAVS ASERFSGDSV IYRPVGEGAP ELVYLGSLSN FDLTYTWVQD
KCVPLVREIT FENGEELTEE GLPFLILFHL KEDSLSLDKF QSEVTRQLIS EKGSINFLHA
DCDKFRHPLL HIQKTPADCP VIAIDSFRHM YVFPDFKDLT IPGKLKQFVL DLHSGKLHRE
FHHGPDPTDS TPGQVGHRFI HRKSAFIMKC CSFSSILTIV LRRRRKRWPA TLQRARSRSW
HLARPATPSS DGTATSCDLS SPAGILRLNA TPRGQGGVRV GTGQRDRRVT PNTLTGKSEK
EDDKKKNKER AAHNIMLE
//
