ID A0A3P9Q562_POERE Unreviewed; 1042 AA.
AC A0A3P9Q562;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Adhesion G-protein coupled receptor G2-like {ECO:0000313|Ensembl:ENSPREP00000029215.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000029215.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000029215.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000029215.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_008425261.1; XM_008427039.2.
DR Ensembl; ENSPRET00000029545.1; ENSPREP00000029215.1; ENSPREG00000019778.1.
DR GeneID; 103475437; -.
DR KEGG; pret:103475437; -.
DR GeneTree; ENSGT00940000164851; -.
DR OMA; LFQGMEV; -.
DR OrthoDB; 4370914at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF264; ADHESION G-PROTEIN COUPLED RECEPTOR G2; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 687..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..742
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..772
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 792..814
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 842..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..911
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 917..940
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 685..941
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 343..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..1006
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 113311 MW; 90D58761150AA63E CRC64;
MEVSCSIKTA INHTKCTIML GLSHKIPSCC ILQTLCAASK RSSDIHVVGN RIDEQNRLQN
QCNSNLGEPN SCIYSGPLDP SCVESGPEYV IPPINLTDCA TGNSCSCSSY CNRSDAYYTF
SISLQDPTIN SSSLSSLISA LAQRPNCSIS TNVTCQSLAT IASEYRNASV DCEMSGTKLS
CRVILGFAQE VSICSVAEAV LNVFVLEEKI QYDGQVRRGA ICGSAEINAN SLDFQFNYTD
SEISPDDFCV KIEGSNLLTC QTGENVVVHL KDQCVVSPTT SPNVTISPNV TSLNTTASPN
VTSLNTTASP XVTLSQNATN PINSTIGPNV TVITNVTTVK PTIQPNNNTL TPTTTPKTQQ
NTTRAPSVPT TAAGGKPSSN ITRSTTSGFV SVTTSVSSTG NGTAESQAKD LLALAQDVSK
LTAAQIDQLV SQLEKLLSGP TVSKELGGLS VNIVSNLLDA SPDKLSSSSD RIIGIVDTVG
LKLVIGNTAE NLLYPSLAVS VKPADGANFQ ETIFSILDPT NVQVRGNPRL KRSALKDSSI
PQGSITLPPS LTQNLTAEEQ KLVSRLQFNF YQKSSLFKDD SLGQRKLNSG ILGASVANLS
IKGLEESVVI RLRNTEPVPA NFVAVCVFWD FTYNKGAGGW NSDGCFVKET NDNETVCGCN
HLTSFAILLD ISRETVTSRT QATILTFITY IGCGLSAIFL FVTLLTYLAF GKLRKDIPSK
ILIQLCLALL LLNLVFLVDA WLALYPKAVG LCISTAWFLH YFLLVSFTWM GLEGVHMYYA
LVKVFNDNIS HYMLKFSLVG WGLPMLVVII VIAIDKNNYG LMSYGKFSDG TSDDFCWIRN
DIAFYVAVVA YFGVIFIFNI VMFGVVLVQL HRIKKQNPHN NKHRSTAQDA RSVIGITLLL
GLTWGFAFFA WGPVNLAFMY LFAIFNSLQG FFIFVFHCAA KETVRRQWRI YLCCGRMRLP
ENLEWSRTAT QKTAKKSPLT SFTSSQSSRP SRSTFLPSTP SGQMSGIGNP LVDRIITADE
EPRTDVVLNE INRQQLRSRR GS
//
