ID A0A3P9Q6X3_POERE Unreviewed; 477 AA.
AC A0A3P9Q6X3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Nuclear factor, erythroid 2 {ECO:0000313|Ensembl:ENSPREP00000029941.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000029941.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000029941.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000029941.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the bZIP family. CNC subfamily.
CC {ECO:0000256|ARBA:ARBA00008157}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P9Q6X3; -.
DR Ensembl; ENSPRET00000030282.1; ENSPREP00000029941.1; ENSPREG00000020275.1.
DR GeneTree; ENSGT00950000182892; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000020275; Expressed in head.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14720; bZIP_NFE2-like; 1.
DR Gene3D; 1.10.880.10; Transcription factor, Skn-1-like, DNA-binding domain; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR004826; bZIP_Maf.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR047167; NFE2-like.
DR InterPro; IPR008917; TF_DNA-bd_sf.
DR PANTHER; PTHR24411; NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR; 1.
DR PANTHER; PTHR24411:SF26; TRANSCRIPTION FACTOR NF-E2 45 KDA SUBUNIT; 1.
DR Pfam; PF03131; bZIP_Maf; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF47454; A DNA-binding domain in eukaryotic transcription factors; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 370..433
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 189..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 388..422
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 305..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 477 AA; 53245 MW; 1CF965944832FB2E CRC64;
MYFVYYYKCC VSLHKVVATP GRLCGGLSMP ANFNGVKPHG PPQDMEMDMA WQELMAITEL
QEFEVQSGNP YEATHYQPMQ PMAPAGEFGM TQSHSEPPPA ACELSTADTY EGCYSEEVPT
CHRLNNTDAV YGNADSQLPH RMLPISSHPQ PSLINMAGTA QGHRRPNASI SQGLSRHMLW
TTLGQNAHVR SGDDLESDSG LSLGSSPPLA SPDNPAGGGP GYQNVDMGTQ YSDCEPESMT
EHGRRGHIHY PMDYQSQTLP YLHSGGHAPY FSPQPSYSHS QTCSMNPRPL KQPVTADVYG
NATVTSRGSS YSMHTKSQGS SSTPAPLSRD ERKAVALKIP FPLDKIINLP VDDFNELLTQ
YTLTDTQLAL VRDIRRRGKN KVAAQNCRKR KLESIVHLER ELNHLQAQRE HLAQERLEFQ
RSLTFIKCRL TDLYREVFSH LRDEDGQPYS IDEYSLQQTP DGSIYLVPHS MDKRDQC
//
