ID A0A3P9Q9E6_POERE Unreviewed; 670 AA.
AC A0A3P9Q9E6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Elongation factor for RNA polymerase II 2 {ECO:0000313|Ensembl:ENSPREP00000030782.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000030782.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000030782.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000030782.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ELL/occludin family.
CC {ECO:0000256|ARBA:ARBA00009171, ECO:0000256|PROSITE-ProRule:PRU01324}.
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DR RefSeq; XP_008407685.1; XM_008409463.2.
DR AlphaFoldDB; A0A3P9Q9E6; -.
DR STRING; 8081.ENSPREP00000030782; -.
DR Ensembl; ENSPRET00000031132.1; ENSPREP00000030782.1; ENSPREG00000020843.1.
DR GeneID; 103464992; -.
DR KEGG; pret:103464992; -.
DR CTD; 22936; -.
DR GeneTree; ENSGT00940000154828; -.
DR OMA; PNYYEEK; -.
DR OrthoDB; 2910197at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000020843; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0008023; C:transcription elongation factor complex; IEA:InterPro.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.140.340; -; 1.
DR Gene3D; 1.10.10.2670; E3 ubiquitin-protein ligase; 1.
DR InterPro; IPR042065; E3_ELL-like.
DR InterPro; IPR031176; ELL/occludin.
DR InterPro; IPR019464; ELL_N.
DR InterPro; IPR010844; Occludin_ELL.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23288; OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL; 1.
DR PANTHER; PTHR23288:SF8; RNA POLYMERASE II ELONGATION FACTOR ELL2; 1.
DR Pfam; PF10390; ELL; 1.
DR Pfam; PF07303; Occludin_ELL; 1.
DR SUPFAM; SSF144292; occludin/ELL-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51980; OCEL; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 556..666
FT /note="OCEL"
FT /evidence="ECO:0000259|PROSITE:PS51980"
FT REGION 165..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..390
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 75087 MW; E8503EE985982E78 CRC64;
MLRLQRDDGG GLVKMAALSE DGRYGLNCGQ QGAERVSVLH VKLTETALRA IENYQSSSNI
PSSRPTVQFK GLQGHIKIPR TESSDTFHNF DFYLSNVGKD NPQGSFECIH QYVSSSGASH
LALLATVQDK VTVCATNDSY QVTRERMTQA VEDTRERGTK VIKPGGQYRG KQVHTRKPAL
SAPDVVPERK RSTPINPANT IRKCLSNNPV SQRPLRDRII HLLALKSYKK LEVLGRLQRD
GINQKDRNSL GTTLQQVANL NPKDNTYSLK EFIYRDVQRD WPGYSEDEKI QADRILARKL
GLPTERVSSN SSPKDGFPSS PQKRQADFDF IDPLAPKKAR ISHLSSRGPA ASSSDRREDE
SSPRSKHSSL PPSVTSGPPT HLPIPSHPPA HQQLSPASNS NSPSTPEGCG TQDLPMDQSS
SCRDPSPSPF SRSLQERCPH PAPRAAASPS PPPCTSLIVT STVVTSPPLS SSTSKKFKKK
SKKHKDKDRE WAKGKQTERA CSSSSPVAVA EESHTVRKRR SAEEVIEEAV EKNPYKDQVK
EKPVHSSESS SKTDMPDYVV KYAPLASLNQ RQSYKNDFNA EYDEYRQLHA RVEGITRRFT
QLDAQCRKLV PGTKEHQKVQ EEVLKEYKKM KQHNPNYHEE KQRCEYLHNK LAHIKRLIAD
FDQRRAQAWC
//
