ID A0A3P9QDX7_POERE Unreviewed; 457 AA.
AC A0A3P9QDX7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Solute carrier family 29 member 2 {ECO:0000313|Ensembl:ENSPREP00000032367.1};
GN Name=SLC29A2 {ECO:0000313|Ensembl:ENSPREP00000032367.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000032367.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000032367.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000032367.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR RefSeq; XP_008433281.1; XM_008435059.2.
DR RefSeq; XP_008433282.1; XM_008435060.2.
DR AlphaFoldDB; A0A3P9QDX7; -.
DR Ensembl; ENSPRET00000032731.1; ENSPREP00000032367.1; ENSPREG00000021932.1.
DR GeneID; 103480187; -.
DR KEGG; pret:103480187; -.
DR CTD; 3177; -.
DR GeneTree; ENSGT00950000182898; -.
DR OMA; FNIMDWV; -.
DR OrthoDB; 517168at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000021932; Expressed in head and 1 other cell type or tissue.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015213; F:uridine transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR034764; ENT1/ENT2.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00939; 2a57; 1.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF8; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 2.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 457 AA; 50396 MW; 457E85E5E58A1F6E CRC64;
MTGRTDTPQD RFCLVGIFFF ILGLGTLLPW NFFMTASLYF QSRLNNTETN GTVVRKEYHF
NNWMTFLSQL PLLVFTLLNS FMYQRISEAI RIAGSLVFIL LLFILTAVLV KVDMHADLFF
SVTMATIWFI NSFGAVLQGS LFGLVGLLPQ KYSTVFMSGQ GLAGTFAAIA MLLAKASEAD
SESAALGYFI TPCVGTLVTL LSYLLLPRLE FAQFYLNRSS KYEEGTTDKL LTVGTPLENG
KLNGHANGAV ASVALGSSGQ DEAKLETSPD RSEQADSSAE KSSVLEVFKK IWVMAFCVTF
VFTVTLSVFP AVTADVKTAF PGGKWEHVFI EVCCFLVFNI HDWFGRTITT WIRCPGKESR
VFPALVVSRV IFIPLLMLCN VQKRSYLPIA FSHDAIFALI MALFSLSSGY FVCLSMSYAP
QLVEPKDAET AGALMTFFLA LGLSIGAALS FLLRILV
//
