ID   A0A3P9QFT5_POERE        Unreviewed;       616 AA.
AC   A0A3P9QFT5;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000032949.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000032949.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000032949.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9QFT5; -.
DR   Ensembl; ENSPRET00000033326.1; ENSPREP00000032949.1; ENSPREG00000022335.1.
DR   GeneTree; ENSGT01100000263513; -.
DR   OMA; ICHRMEV; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Bgee; ENSPREG00000022335; Expressed in caudal fin and 1 other cell type or tissue.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638}.
FT   DOMAIN          81..213
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   616 AA;  71428 MW;  B0AAEC3C8FC4DB0B CRC64;
     MFSMFSDFDI RCQQELKEYL KMKFQGLCEG VAEYGSEAVL DQIYTELHIT EGKIETASRK
     QETIRREDIF KVPHGRDQPI RTVITMGVAG IGKTLLTQKF TLDWAEGKTN QDIDFIFPFT
     FKELNLLKEE KFSLLGLIHK LFSKTKGISS FEMFQVLFIF DGLDESRLNL DFQNNEILTD
     VTESSSVDVL VTNLIRGNLL LSAFLWITTR PAAANQIPAQ CVGMVTEVRG FTDPQKEEYF
     RKKFINDDDK AHRIISHIQK SKSLHIMCHI PVFCWITANV LDNVMKTREG GELPKTLTEM
     YIEFLLVQLT IKEDKYSGNA EDPDNRKLIE SLGKLAFDQL LKGNLIFYDK DLKRCGINIK
     DASLFSGVFT QMFKRERGRH NISVYSFVHL SIQEFLAAVY MLHCFTTWRK TKVIKSLLGK
     YYFFISLGEF MKKVMEKSLW SKNGHLDLFV RFLHGLTVES NQRLLEDLLG QTENSSETIQ
     RIITNLKKMN TGRISPDRSI NIFYCLVEMN DLSFTKEIQR LLDSGKELSM TDCSALAFML
     QMSEVVDELD LEKYNTSADI LHCNSEICHR MEVFPPWGKK CNKIHKKLNT KSIKVMNTKK
     YSRHWELKLH SIKVKW
//