ID A0A3P9QG87_POERE Unreviewed; 1239 AA.
AC A0A3P9QG87;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Contactin-associated protein-like 4 {ECO:0000313|Ensembl:ENSPREP00000033109.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000033109.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000033109.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000033109.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR Ensembl; ENSPRET00000033486.1; ENSPREP00000033109.1; ENSPREG00000021986.1.
DR GeneTree; ENSGT00940000160228; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00110; LamG; 3.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 3.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF40; CONTACTIN-ASSOCIATED PROTEIN-LIKE 4; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF02210; Laminin_G_2; 3.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00282; LamG; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS01286; FA58C_2; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 3.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00122}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1239
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018188454"
FT TRANSMEM 1171..1195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..154
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 160..347
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 353..512
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 514..551
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 756..920
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 921..959
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 893..920
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
SQ SEQUENCE 1239 AA; 137366 MW; 4F5958740DFE0C9E CRC64;
TPYIAGCPLQ LLLQLLSGCA EARFPPESEL NRCCCVTGAG AGGWSPLWSD EHQWLEVDLQ
RRTQITAVAT QGRYGSSDWL TTYLLMFSDT GHNWRQHRQE DSLGVKFAFP GNSNADSVVQ
YKLDQPVIAR YLRLIPLDWN PTGRIGLRLE IYGCRYTSEV AGFDGKSSLV YRLSARTSWT
ARESISLKFK TLRNSGTLLH AKGQRDHSLN LALERGKLLL HHQQGTDLSN VSSGSGGKLL
VSLGSLLDDQ HWHHVKLERL GSHLNLTVDR NTQQVLVPAE LSHWHIHTVR PVQSHGLQTP
ILPNRNFHGC MENLLYNDLN LIRLAKQGSP QSFLRLFLLQ GNTTFSCSEP VFVAVTFTGS
HSFLQLPVLT SWLSGVVSIA LQFRTWNKAG LLLTFDLQQQ EGSVFLYCSD VTCCCFCVCV
RSGAGLNDGQ WHSVELNSME NRLSITVDRD EGATAHTSIP LPPAGGGFSC RNPIQGFQGC
MRLLKLDGET VDLIKVQERR LGNYSDLKID MCGIIDRCSP SHCEHGGRCS QSWRNFHCNC
SNSGYRGATC HTKYEPSCEV YKHQGDTSGH FYVDVDGSGP IKPQLVYCNM TGKTTSLKMW
IPFHFTQTCN KLRCCRFVFL YPSEEKQLSA VISQSEHCEQ ELSYHCRKSR LSNSLDGTPF
SWWVGGPASG QIQNFWGEAL PGSRQCACGL QDNCLDSSFY CNCDADYDLW YDSDLLTQKE
SLPVRLLVLG DIHRPGSEAA YRVGPLRCHG DKNFWNAAFF DKETSYLHFP TFHGELNADI
SFLFKTTSSS GLFLENLGIK DFIRIELSSS TEVVFSFDVG NGPLEVKVRS DLPLNDDRWH
SVRAERNVKE ASLRVDDLPA AVREAPTDGF IHLQLNSQLF IGTASRQKGF LGCIRSLQLN
GVTLDLEERA RITPGVRPGC PGHCSSYAAL CQNQGRCVER ASGFSCDCSR SAYTGVFCHE
EVSGSFEPTT SITYIVKEPY EASKNSSSLH SSIYSDITLR GDDVSLSFRT SQSPAPLLYV
SSFYRQYLIL LINKHGEDFC QTKIFCSYNL WPFCSFSYFS LFYGFALSHF GSLSKAISTR
SHQFRKVLEX FGGIFKYHAD LAGLASAGFT GCLSAVRFGS FCPLKAALLR PDGRVSVAGA
VVASSCAAPA QADSYAAETT HSLSGKIRTT AAFPGVIAVV IFIVVCAAAI LARFICIRKE
TYRNQEVKAA QPGDGSAFPF SGQPDSLSVQ SENQKEFFI
//
