ID   A0A3P9QJE0_POERE        Unreviewed;       467 AA.
AC   A0A3P9QJE0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Perforin-1-like {ECO:0000313|Ensembl:ENSPREP00000034214.1};
OS   Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000034214.1, ECO:0000313|Proteomes:UP000242638};
RN   [1] {ECO:0000313|Proteomes:UP000242638}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA   Kuenstner A., Dreyer C.;
RT   "The genomic landscape of the Guanapo guppy.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPREP00000034214.1}
RP   IDENTIFICATION.
RC   STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000034214.1};
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3P9QJE0; -.
DR   Ensembl; ENSPRET00000034595.1; ENSPREP00000034214.1; ENSPREG00000023172.1.
DR   GeneTree; ENSGT00940000164067; -.
DR   Proteomes; UP000242638; Unassembled WGS sequence.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR020864; MACPF.
DR   PANTHER; PTHR46096; PERFORIN-1; 1.
DR   PANTHER; PTHR46096:SF1; ZGC:163021 PROTEIN; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF01823; MACPF; 1.
DR   SMART; SM00457; MACPF; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51412; MACPF_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..467
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017959142"
FT   DOMAIN          28..361
FT                   /note="MACPF"
FT                   /evidence="ECO:0000259|PROSITE:PS51412"
FT   DOMAIN          361..467
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
SQ   SEQUENCE   467 AA;  52065 MW;  E802D5EE3BF4AAC5 CRC64;
     MLPDSTSALL LLSVLLVHSS VLSCRIGTQK ECDAAPFAPG HDLVGEGFDI VTLERKRLHV
     IDVTTYLSPS KTCKLCTNPL QKHALQKLPS SVVDWSYKNM VSYLTPYKLN VLSVFHQVGL
     KVQMFVFAGL DAGATRSNAY KFVSQRSKED RYTFSIHSVA CSHYGLILSN TPPLTLKFKK
     RLDLLPSHYN NSTKNEFRKL INTYGTHYFR MVNIGGRLRR LISSRSCLAS LNGLNIHSCL
     SMGIAVGLGK VKISSVQKSC IGVLKNLDSA TNFSSGLHQN FTEVSGGNGW LGEFSIFQND
     SIDYMNWLKS LKEQPDVVSH SLRPLYELVP NELQKAAVKA AIEQYLKDNA VKKSPKEPHC
     EGKTPNVASN CCPQHASWGT LSVTIVRGRD LFGDELSLTD GYAKMYYGSI QRKTKIIESN
     NPQWNAEFNL GNRPLFLKTS NFPCCLQSSY QNPRDLNNKK IKIKNLG
//