ID A0A3P9QJS3_POERE Unreviewed; 818 AA.
AC A0A3P9QJS3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Taste receptor type 1 member 1-like {ECO:0000313|Ensembl:ENSPREP00000033973.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000033973.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000033973.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000033973.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3P9QJS3; -.
DR STRING; 8081.ENSPREP00000033973; -.
DR Ensembl; ENSPRET00000034353.1; ENSPREP00000033973.1; ENSPREG00000023012.1.
DR GeneTree; ENSGT00940000156136; -.
DR OMA; STCLCRQ; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15287; 7tmC_TAS1R2a-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00592; CASENSINGR.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..818
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017986855"
FT TRANSMEM 546..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 701..727
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..761
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 767..787
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 545..803
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 818 AA; 92799 MW; 26CE2CF9AB977E28 CRC64;
MTHFIAAVCL MGLFLQGITK STLRHSEFQL EGDYLLGGLF DIHYISSPPS QKRPEAIDCS
REIFLLPNYR RFQLMRFTVE EINNSTTLLP NVTLGYELFD HCSDTRSFTD IFKLISVNDS
IQPWHEPSKN RSKLIALVGP FTSTHALTVA PFFMVDHIPV VSYGSSASVF SEKRKYPSFL
RTVHPNQDTV GVIVMILQHF DWRWVAFLHS GDDFGSDGLE MFIQRIKTTD ICLAYSKALS
EDTDYSLVFK QMEEQKLNVI IVFAPKIYAE AIIKTAIEQN VTNKVWIADD GWSLNKQLAK
LEGIGNIGTV LGVAQPVVTI PGFDDFIYFT AERALKADAE QQMLCNQDCN CRNLTAGKII
AADPSFSFPI YSAVHAVARA LHNILKCETG RCDDAIPVQP FMVQLRRSNF TLLNQSVLFD
ENGDPNFGHF SIVFWNHSGD AQEVGFYHFN QSPAFYINNT QIQWHTGGEV PIAICSPECP
TGYARKITGI HKCCFRCEIC PPETYVNITD DPYNCISCKE TEWSKEGSTS CSLRLVEYVP
FTDRRAILVM AGTIIFLGLI LAVALLFAVN YHTPVVRSAG GAMCFLILGC LTLCSVSVFF
FFGKPTNATC VLRYFPFVLC YSVCLACFVV RSFQIVCIFK IAAKFPKLQS WWIKYHGQWL
LITGTFSTQA MLILISFSFY PPRPYNETSW YQDQIVLSCD LNLAAASCSF IILPFLCCLC
FIFSYMGKDL PKNYNEAKAI TFCLLLLILT WIMFATEYLL YRGKYIHTLN ALAVLSSLYS
FLLWYFVPKC YIMIFQAHKN TQKYFQGLIQ NYTKTISQ
//
