ID A0A3P9QJX2_POERE Unreviewed; 165 AA.
AC A0A3P9QJX2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Adrenomedullin {ECO:0000313|Ensembl:ENSPREP00000034108.1};
OS Poecilia reticulata (Guppy) (Acanthophacelus reticulatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=8081 {ECO:0000313|Ensembl:ENSPREP00000034108.1, ECO:0000313|Proteomes:UP000242638};
RN [1] {ECO:0000313|Proteomes:UP000242638}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Guanapo {ECO:0000313|Proteomes:UP000242638};
RA Kuenstner A., Dreyer C.;
RT "The genomic landscape of the Guanapo guppy.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPREP00000034108.1}
RP IDENTIFICATION.
RC STRAIN=Guanapo {ECO:0000313|Ensembl:ENSPREP00000034108.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the adrenomedullin family.
CC {ECO:0000256|ARBA:ARBA00010575}.
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DR RefSeq; XP_008403494.1; XM_008405272.2.
DR AlphaFoldDB; A0A3P9QJX2; -.
DR STRING; 8081.ENSPREP00000034108; -.
DR Ensembl; ENSPRET00000034488.1; ENSPREP00000034108.1; ENSPREG00000023101.1.
DR GeneID; 103462466; -.
DR KEGG; pret:103462466; -.
DR CTD; 556502; -.
DR GeneTree; ENSGT00940000154380; -.
DR OMA; QSFLYCC; -.
DR OrthoDB; 4548241at2759; -.
DR Proteomes; UP000242638; Unassembled WGS sequence.
DR Bgee; ENSPREG00000023101; Expressed in caudal fin and 1 other cell type or tissue.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR InterPro; IPR021116; Calcitonin/adrenomedullin.
DR PANTHER; PTHR23414; ADRENOMEDULLIN, ADM; 1.
DR PANTHER; PTHR23414:SF3; PRO-ADRENOMEDULLIN; 1.
DR Pfam; PF00214; Calc_CGRP_IAPP; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR621116-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000242638};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..165
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018024289"
FT DISULFID 87..92
FT /evidence="ECO:0000256|PIRSR:PIRSR621116-50"
SQ SEQUENCE 165 AA; 19036 MW; A5DEF1C8FFEF0DC9 CRC64;
MKTIFHSFLY CCLLASVAHC VELEVNPELK KRLSIWLGSR LRRDLETVAV QKTAESENFV
RPEDIRDILL PHSSTDIKIR TKRSAGCALG TCSVHVLAHR VQQFKDNKLK TSVPINKMSP
HGYGRRRRSV PERQISLRME EGRLRPVWSL NNSQVHKLEA LLRRT
//
