ID A0A3Q0CH77_MESAU Unreviewed; 368 AA.
AC A0A3Q0CH77;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Integrin alpha-7-like isoform X2 {ECO:0000313|RefSeq:XP_021079873.1};
GN Name=LOC101842593 {ECO:0000313|RefSeq:XP_021079873.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021079873.1};
RN [1] {ECO:0000313|RefSeq:XP_021079873.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28071753;
RA McCann K.E., Sinkiewicz D.M., Norvelle A., Huhman K.L.;
RT "De novo assembly, annotation, and characterization of the whole brain
RT transcriptome of male and female Syrian hamsters.";
RL Sci. Rep. 7:40472-40472(2017).
RN [2] {ECO:0000313|RefSeq:XP_021079873.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_021079873.1; XM_021224214.1.
DR AlphaFoldDB; A0A3Q0CH77; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF90; INTEGRIN ALPHA-7; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037,
KW ECO:0000313|RefSeq:XP_021079873.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 54..275
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
FT REGION 159..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 40697 MW; 903AB97592FA9B7B CRC64;
MKRGAQVTFY LLLSTSGITI ETTELEVELL LATISEQELH PVSVRAQVFI ELPLSISGVA
TPQQLFFSGV VKGESAMRSE RDVGSKVKYE ITVSNQGQSL NTLGSAFLNI MWPHEIANGK
WLLYPMRVEL EGGQGPGKKG ICSPRPNILH LDVDSRDRRR RELEQEQREP QEPPEKLEPS
STSWWPVSSA ERKRNVTLDC AQGTAKCVVF SCPLYSFDRV AVLHVWGRLW NSTFLEEYIA
VKSLEVIVRA NITVKSSIKN LLLRDASTTI PVMVYLDPVA VVAEGVPWWV ILLAVLAGLL
VLALLVLLLW KCGFFHRNSP SSSVPTNYHR AHLAVQPSAM EVGGPGTVGW DSSSAPSTPR
LLCPSTTR
//
