ID A0A3Q0CHX6_MESAU Unreviewed; 242 AA.
AC A0A3Q0CHX6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=H-2 class I histocompatibility antigen, Q9 alpha chain-like {ECO:0000313|RefSeq:XP_021080207.1};
GN Name=LOC101835748 {ECO:0000313|RefSeq:XP_021080207.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021080207.1};
RN [1] {ECO:0000313|RefSeq:XP_021080207.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in the presentation of foreign antigens to the
CC immune system. {ECO:0000256|ARBA:ARBA00002297}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the MHC class I family.
CC {ECO:0000256|ARBA:ARBA00006909, ECO:0000256|RuleBase:RU004439}.
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DR RefSeq; XP_021080207.1; XM_021224548.1.
DR AlphaFoldDB; A0A3Q0CHX6; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0098553; C:lumenal side of endoplasmic reticulum membrane; IEA:UniProt.
DR GO; GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
DR GO; GO:0030670; C:phagocytic vesicle membrane; IEA:UniProt.
DR GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR InterPro; IPR011161; MHC_I-like_Ag-recog.
DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR001039; MHC_I_a_a1/a2.
DR PANTHER; PTHR16675:SF242; CLASS IB MHC ANTIGEN QA-2-RELATED; 1.
DR PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR Pfam; PF00129; MHC_I; 1.
DR PRINTS; PR01638; MHCCLASSI.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunity {ECO:0000256|ARBA:ARBA00022451};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW MHC I {ECO:0000256|ARBA:ARBA00022451};
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 61..239
FT /note="MHC class I-like antigen recognition-like"
FT /evidence="ECO:0000259|Pfam:PF00129"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..35
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 242
FT /evidence="ECO:0000313|RefSeq:XP_021080207.1"
SQ SEQUENCE 242 AA; 27143 MW; 6750921F416CC98F CRC64;
MASGGRSGVA PGKPCPHIAQ PDPPAPSPPT SPALRPAPLQ ARAPAQGPGR RSGSQSTQPS
GSHSLRYFYT TVSRPGLGEP RFIVVRYVDD TQFVRFDSDA ENPRYETVAP WMEREGPDYW
ERQTRIARDN EQIYRGNLRT LLGYHNQSEG GSHTFQHLSG CHVGSDGRLQ RGYEHFAYDG
NDYIALNDDL RTWSAADTVA QITWLKWEQD GTAERHRAYP ESTCMELLLR HLETGKEQLL
HT
//
