ID A0A3Q0CIE5_MESAU Unreviewed; 1747 AA.
AC A0A3Q0CIE5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Sorbin and SH3 domain-containing protein 1 isoform X13 {ECO:0000313|RefSeq:XP_021080263.1};
GN Name=Sorbs1 {ECO:0000313|RefSeq:XP_021080263.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021080263.1};
RN [1] {ECO:0000313|RefSeq:XP_021080263.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26319212;
RA Ying B., Toth K., Spencer J.F., Aurora R., Wold W.S.;
RT "Transcriptome sequencing and development of an expression microarray
RT platform for liver infection in adenovirus type 5-infected Syrian golden
RT hamsters.";
RL Virology 485:305-312(2015).
RN [2] {ECO:0000313|RefSeq:XP_021080263.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_021080263.1; XM_021224604.1.
DR Proteomes; UP000189706; Unplaced.
DR CDD; cd11919; SH3_Sorbs1_1; 1.
DR CDD; cd11922; SH3_Sorbs1_2; 1.
DR CDD; cd11916; SH3_Sorbs1_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR InterPro; IPR035606; SORBS1_SH3.
DR InterPro; IPR035610; SORBS1_SH3_1.
DR InterPro; IPR035611; SORBS1_SH3_2.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 297..400
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 1211..1270
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1285..1346
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1686..1747
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1023..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1487..1559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1653..1685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..184
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..464
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1003
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1072..1086
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1110..1124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1503..1532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1533..1549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1660..1685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1747 AA; 192682 MW; DD35A83163BFCE30 CRC64;
MSSECDVGSS KAVVNGLAPG SHVQDKATAD PLRARSVSAV KIIPVKTLKS PSGLVLPPDM
DPTKICTGKG TVTLRASSSY RETPSSSPVS PQESPKHESK SGLEPEEDPS ADERRLSSSA
DANGNAQPSP LAAKGYRSVH PSLSTDKPQR RPHHSQPASA CGSLPPASQR PPPSPPPPLV
PPIPEDLHRA LEPDLPGAVS STGSPLINEV SSSHIETDSQ AFLPTSKPSS AYPSTTIVNP
TIVLLQHNRE QQKRLSSISD PASERRVGEQ DSVPTPAELT SPSRAAERRA KDDSRRVVKS
AQDLSDVSMD EVGIPLRNTE RSKDWYKTMF KQIHKLNRDT PEENPYFPTY KFPELPEILQ
NSEEDNPYTP TYQFPASTPS PKSEDDDSDL HSPRYSYSED TKSPLSVPRS KSEMNYIDGE
KVVKRSATLP LPARSSSLKS SPERNDWEPP DKKVDTRKYR AEPKSIYEYQ PGKSSVLTNE
KMSRDISPEE IDLKNEPWYK FFSELEFGKP PPKKIWDYTP GDCSILPRED RKTNLEKDLS
FSQAELEADL EKVETVNKSP SANPPQSSAI SPDVTPEPPG YIYSSNFHAV KREPDGTPGV
LASLENERQI YKSVLEGGDI PLQGLSGLKR PSSSASTKVD RKGGNAHMIS SSSVHSRTFH
TSNALGPGCK HKKPLSAAKA CISEILPSKF KPRLSAPSAL LQEQKSVLLP SEKAQSCENL
CVSLSDSKRG LPLRVGGSIE NLLMRSRRDY DSRSSSTMSL QEYGTSARRP CPLSRKAGLH
FSMFYRDMHQ INRAGLSLGS ISSSSVRDLA SHFERSSLAL ARGELGASQE GSEHIPKHTV
SSRITAFEQL IQRSRSMPSL DFSGRLSKSP TPVLSRSGLI SARSAESLLE STKLRPREID
GMNSGGAFAS PTCSNMADHA LSFRSLVPSE PHSVCSDELD HCSNASNDSR EGSGGSAHGD
FPKHRLNKCK GACPASYTRF TTIRKHEQQS SRQPDWRSDS RGDKNSVLRN IYLMSPLPFR
LKKPLQHHPR QPPPNDSSGP PAGQKADLPS QGPQDQPHSA GKPVVPTRLS SRHTMARLSH
NSEPSLDRSA GLEDCTGAIN NGNPVPYSDH GLDRNNNPQS ELAAARGDSE SPRHFIPADY
LESAEEFIRR RHDDKEKLLA DQRRLKREQE EADIAARRHT GVIPTHHQFI TNERFGDLLN
IDDTAKRKSG LEMRPARAKF DFKAQTLKEL PLQKGDIVYI YKQIDQNWYE GEHHGRVGIF
PRTYIELLPP AEKAQPRKLA PVQVLEYGEA IAKFNFNGDT QVEMSFRKGE RITLLRQVDE
NWYEGRIPGT SRQGIFPITY VDVLKRPLVK NPVDYIDLPY SSSPSRSTTA SPQYTSHSKL
IMPAPSSLPH PRRALSPEMH AITSEWISLT VGVPGRRSLA MTPPLPPLPE ASVYDTDHLA
LSARVRPSLP LSLPYSSRSD HSTLRSVVSP LALPSPHKAY SLAPGAQAPL HINGDGGIHT
HQEGFSQPPQ GNSDRVISEL SDAFSSQSKR QSWREDGSYE RRAESEAGER YPGGPKISKK
NCLRPSDVVR CLSSEQRLSE FHTPDDSQSF KPLGSPFPAW EAGPPELHRG VEADRKAAQS
GVSQEAVCNE IINIAEKSVH YCSTVSHPLD FHHKVPPSDS KSSLIVSQQP QAQQRRVTPD
RSQTSQDLCS YQALYSYVPQ NDDELELRDG DIVDVMEKCD DGWFVGTSRR TRQFGTFPGN
YVKPLYL
//
