ID   A0A3Q0CK65_MESAU        Unreviewed;      1515 AA.
AC   A0A3Q0CK65;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=EF-hand calcium-binding domain-containing protein 6 {ECO:0000313|RefSeq:XP_021081077.1};
GN   Name=Efcab6 {ECO:0000313|RefSeq:XP_021081077.1};
OS   Mesocricetus auratus (Golden hamster).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Mesocricetus.
OX   NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021081077.1};
RN   [1] {ECO:0000313|RefSeq:XP_021081077.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=28071753;
RA   McCann K.E., Sinkiewicz D.M., Norvelle A., Huhman K.L.;
RT   "De novo assembly, annotation, and characterization of the whole brain
RT   transcriptome of male and female Syrian hamsters.";
RL   Sci. Rep. 7:40472-40472(2017).
RN   [2] {ECO:0000313|RefSeq:XP_021081077.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_021081077.1; XM_021225418.1.
DR   STRING; 10036.ENSMAUP00000018022; -.
DR   Proteomes; UP000189706; Unplaced.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 12.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR015070; EF_hand_DJBP.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR20875; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED; 1.
DR   PANTHER; PTHR20875:SF0; GH12158P; 1.
DR   Pfam; PF08976; EF-hand_11; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 10.
DR   SUPFAM; SSF47473; EF-hand; 7.
DR   PROSITE; PS00018; EF_HAND_1; 3.
DR   PROSITE; PS50222; EF_HAND_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT   DOMAIN          97..132
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          199..234
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          902..937
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1085..1120
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1192..1227
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1453..1483
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          607..630
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1047..1067
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1259..1317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1275..1317
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1515 AA;  174760 MW;  9760006B9E0EE3B2 CRC64;
     MRRNNVKLNV AKANSTRSGS TKARDLMHRM SILPDWHSLY SRTQKLTCSR PHSSPCKEHL
     KTSCQDLCRP SSSATAFVNP VLSFLDVERI LSQKISNKKD EMRKVFQVLD PTHRQTVTKG
     ELKRVITAFL LPLTREQFQD LLAQIPLTSS GNVPYLEFLS RFGGIDLNIN VIKRGNGNEI
     DYSRTIKEFE AQLIEKIFRN MKTLEKVFHL IDVNNTGVVQ SQELRRVLEI FCLKMKDEEY
     EMFLKEYNIS GTTAVDYNAF LKNLSVSNDS NFRHLLSSSE ISRENQQAKT GRRERPLNSV
     SSEDVWKNYS LDDVEKTFCQ ELSKSYEKIE KALSAGDPSK GGYVSLNYLK VVLDTFVYVL
     PRRIFIQLMK RFGLKTTTKV NWKQFLTAFY ERQGLGVSKA IPLKKRSSVD SRNQSRKENI
     IKKLFRYSEE RYTALKKALL IISTTPNGHM TWEELRHILN CMVAKLNDSE FYELKQTFDP
     EGTGAVKVSS LLEALDDSPK VRKMSPSTDT KAPLPVAWDS VEEMVLDAIT KNLQTFYGML
     QSYDLGDTGT IARNNFKKVM RIFCPYLSNE HFVKLSSKFQ DTASGRIQYK KLLLSIGISV
     PPPTSPFSVL KDQLSEQNEE QDPPDLAERT QPVTDKTMTK EEVIDRLKQC IQQQDPVFKK
     QFLSISKQPD AKIGLEDFRK VLEESGMPMN DSQYDMLISK IGYKKEGMSY QDFTSGFEDT
     KLSGLETVPQ QSRTASKTNL DDRFTSAEEC LRLFPKKLKE LFRDPYSAFF KVDTDMDGII
     NMHDLHRLLQ QLQLYMKDSE FERFLSLLGL RLSITLNFRE FQNLCEKKPW KSDEAPQRLL
     RYKQKVADSE LACEQAHQYL VIKAKTRWAD LSKNFIETDN EGNGILRRRD IKNALYGFDI
     PLTPREFEKL WQNYDIEGRG YITYQEFLQR LGIRYSSKVH RPYKEDYFNF LGHFTKPKQI
     QEEIQELQQM TEREKLMDHY EEISKALNML EKSKPGSAAL CKVQKVLQDC GCPLKEEELI
     TLLKSLGISV HNNSINPLDL LRALETSKTS KAQPKEKEEG TPTPINFSML NPEEVVKNMQ
     VVVDSSQSAL LKAFSALDKE DTGFVKAMDF GDVLKSFCLK LTDNQYHYFL RKLRIHLTPH
     IHWKYFLENF SSFMEEAADE WAEKMPKVPT PTSPKEMANR DILSRVHKAV ASHYHTIVQE
     FENFDTTKSN TVSRDEFRSI CTRHVQILTD EQFDRLWSEM PVNAKGRLKY QDFLSKFSTE
     RLPSPPMDAG DSGDSTMAQR GSSAPEVSQG TRSTLCSPSQ DPRAGLKSQS HPCTPVGTPP
     LQNCEPIESK LRKQIQGCWR ELLKECKEKD SDKQGSVTAA EFLALVEKFK LDISKEESQQ
     LIVKYDLKNN GKFAYCDFIQ SCVLLLKAKE TSLMRRMRIQ NADKMKEAGV ETQSFYSALL
     RIQPKIVHCW RPMRRTFKAY DENGTGLLSV ADFRKVLRQY SINLSEEEFF HVLEYYDKSL
     SSKISYNDFL RAFLQ
//