ID A0A3Q0CL53_MESAU Unreviewed; 461 AA.
AC A0A3Q0CL53;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Interferon regulatory factor 4 isoform X2 {ECO:0000313|RefSeq:XP_021080689.1};
GN Name=Irf4 {ECO:0000313|RefSeq:XP_021080689.1};
OS Mesocricetus auratus (Golden hamster).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Mesocricetus.
OX NCBI_TaxID=10036 {ECO:0000313|Proteomes:UP000189706, ECO:0000313|RefSeq:XP_021080689.1};
RN [1] {ECO:0000313|RefSeq:XP_021080689.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_021080689.1; XM_021225030.1.
DR AlphaFoldDB; A0A3Q0CL53; -.
DR Proteomes; UP000189706; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF6; INTERFERON REGULATORY FACTOR 4; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000189706}.
FT DOMAIN 21..129
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 461 AA; 52776 MW; AEEDF639FC8CB730 CRC64;
MNLEAGSRGA EFGMSAVSCG NGKLRQWLID QIDSGKYPGL VWENEEKSVF RIPWKHAGKQ
DYNREEDAAL FKAWALFKGK FREGIDKPDP PTWKTRLRCA LNKSNDFEEL VERSQLDISD
PYKVYRIVPE GAKKGAKQLT LEDTQMAMGH PYPMAAPYGS LPAQVHNYMM PPHDRSWRDY
APDQSHPEIP YQCPVTFGPR SHHWQGPSCE NGCQVTGTFY ACAPPESQAP GIPIEPSIRS
AEALALSGPI STDSRVLFTD CRLHIYLYYR DILVKELTTS SPEGCRISHG HTYDVSNLDQ
VLFPYPEDNG QRKNIEKLLS HLERGLVLWM APDGLYAKRL CQSRIYWDGP LALCNDRPNK
LERDQTCKLF DTQQFLSELQ VFAHHGRPEP RFRVTLCFGE EFPDPQRQRK LITAHVEPLL
AKQLFYFAHQ NSGHFPRGYD ISEHISTPDY HRSLRHSSIQ E
//
